Trandolaprilat Acyl-D-glucuronide is a metabolite of the angiotensin-converting enzyme (ACE) inhibitor trandolapril, which is used primarily in the treatment of hypertension and heart failure. This compound is characterized by its glucuronidation, a process that enhances the solubility and excretion of the drug. The acyl-D-glucuronide structure indicates that it has undergone conjugation with glucuronic acid, which is a common phase II metabolic reaction that facilitates drug elimination. The presence of the glucuronide moiety typically enhances the compound's polarity, affecting its pharmacokinetics and bioavailability. Trandolaprilat itself is known for its potent antihypertensive effects, and its glucuronide derivative may exhibit altered pharmacological properties compared to the parent compound. The specific percentage mentioned (65%) likely refers to the purity or concentration of the substance in a given formulation. As with many drug metabolites, the safety and efficacy profile can differ from the parent drug, necessitating careful consideration in therapeutic contexts.

Trandolaprilat Acyl--D-glucuronide, 65%

1260610-97-6: Trandolaprilat Acyl-D-glucuronide is a metabolite of the angiotensin-converting enzyme (ACE) inhibitor trandolapril, which is used primarily in the treatment of hypertension and heart failure. This compound is characterized by its glucuronidation, a process that enhances the solubility and excretion of the drug. The acyl-D-glucuronide structure indicates that it has undergone conjugation with glucuronic acid, which is a common phase II metabolic reaction that facilitates drug elimination. The presence of the glucuronide moiety typically enhances the compound's polarity, affecting its pharmacokinetics and bioavailability. Trandolaprilat itself is known for its potent antihypertensive effects, and its glucuronide derivative may exhibit altered pharmacological properties compared to the parent compound. The specific percentage mentioned (65%) likely refers to the purity or concentration of the substance in a given formulation. As with many drug metabolites, the safety and efficacy profile can differ from the parent drug, necessitating careful consideration in therapeutic contexts.

<p>Trandolaprilat acyl-D-glucuronide is a synthetic compound that has been designed for the treatment of hypertension. Trandolaprilat acyl-D-glucuronide is an active metabolite of trandolapril, which is a prodrug of trandolaprilat. Trandolaprilat acyl-D-glucuronide is glycosylated and has high purity with low impurities. It can be custom synthesized to meet your requirements. The CAS number for this compound is 1260610-97-6.</p>

CAS 1260610-97-6

Trandolaprilat Acyl--D-glucuronide, 65%

Trandolaprilat acyl-D-glucuronide

Ref: 3D-MT09947