CAS 1260618-73-2

Fmoc-2,3-difluoro-D-homophenylalanine

Description:

Fmoc-2,3-difluoro-D-homophenylalanine is a synthetic amino acid derivative characterized by the presence of a fluorinated phenylalanine structure. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective moiety for the amino group, facilitating its use in peptide synthesis by preventing unwanted reactions during the coupling process. The presence of two fluorine atoms at the 2 and 3 positions of the aromatic ring enhances the compound's lipophilicity and may influence its biological activity and interactions. This compound is typically utilized in the field of medicinal chemistry and peptide synthesis, particularly in the development of novel therapeutics. Its unique structural features can affect the conformation and stability of peptides, making it a valuable building block in the design of bioactive molecules. As with many fluorinated compounds, Fmoc-2,3-difluoro-D-homophenylalanine may exhibit distinct physicochemical properties, such as altered solubility and reactivity, which can be advantageous in specific applications.

Formula: C₂₅H₂₁F₂NO₄

Synonyms:

• Fmoc-2,3-difluoro-D-homophenylalanine
• Fmoc-D-HomoPhe(2,3-Difluoro)-OH
• Benzenebutanoic acid, α-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2,3-difluoro-, (αR)-
• (2R)-2-amino-4-[4-(trifluoromethyl)phenyl]butanoic acid
• (2R)-4-(2,3-difluorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid