CAS 126138-81-6

8-(Allyloxy)guanosine

Description:

8-(Allyloxy)guanosine is a modified nucleoside that features a guanine base linked to a ribose sugar, with an allyloxy group attached at the 8-position of the guanine moiety. This modification can influence the nucleoside's biochemical properties, such as its solubility, stability, and interaction with enzymes and receptors. The presence of the allyloxy group may enhance its lipophilicity, potentially affecting its cellular uptake and biological activity. As a nucleoside analog, 8-(Allyloxy)guanosine may be of interest in research related to nucleic acid chemistry, antiviral drug development, or as a tool in molecular biology for studying RNA and DNA processes. Its unique structure allows for potential applications in therapeutic contexts, particularly in the modulation of nucleic acid functions. However, specific biological activities and mechanisms of action would require further investigation through experimental studies. Overall, 8-(Allyloxy)guanosine represents a valuable compound for exploring the interplay between nucleoside structure and function in biochemical systems.

Formula: C₁₃H₁₇N₅O₆

InChI: InChI=1/C13H17N5O6/c1-2-3-23-13-15-6-9(16-12(14)17-10(6)22)18(13)11-8(21)7(20)5(4-19)24-11/h2,5,7-8,11,19-21H,1,3-4H2,(H3,14,16,17,22)/t5-,7?,8+,11-/m1/s1

Synonyms:

• 8-(2-Propenyloxy)guanosine

8-Allyloxyguanosine

CAS: 126138-81-6

Formula: C₁₃H₁₇N₅O₆

Color and Shape: Solid

Molecular weight: 339.3040

Ref: IN-DA000RQY

8-(Allyloxy)guanosine

CAS: 126138-81-6

Ref: 7W-GN5606

8-Allyloxyguanosine

CAS: 126138-81-6

8-Allyloxyguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.

Formula: C₁₃H₁₇N₅O₆

Color and Shape: Solid

Molecular weight: 339.3

Ref: TM-TNU0340

8-(Allyloxy)guanosine

CAS: 126138-81-6

8-(Allyloxy)guanosine is a nucleoside analog. It is an antiviral and anticancer drug that inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. 8-AOG also inhibits the expression of genes involved in inflammatory responses, such as lipoxygenase, cyclooxygenase 2, and 5-lipoxygenase. This compound has been shown to be effective against herpes simplex virus types 1 and 2, cytomegalovirus, Epstein-Barr virus, adenovirus type 3, and human immunodeficiency virus type 1 (HIV-1). 8-(Allyloxy)guanosine can be used to inhibit the tumor growth of human cancer cells in vitro.
8-(Allyloxy)guanosine has been shown to have a low toxicity to healthy cells in vitro and when administered in vivo.

Formula: C₁₃H₁₇N₅O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 339.3 g/mol

Ref: 3D-NA16502