Rizatriptan N10-Oxide-d6 is a deuterated derivative of rizatriptan, a medication primarily used for the acute treatment of migraine attacks. The "N10-Oxide" designation indicates that the nitrogen atom in the 10 position of the rizatriptan structure has been oxidized, which can influence the compound's pharmacological properties. The "d6" suffix signifies that the compound is deuterated, meaning that six hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its metabolic pathways, making it useful in research applications, particularly in pharmacokinetics and drug metabolism studies. Rizatriptan itself is a selective agonist for serotonin receptors, specifically the 5-HT_1B and 5-HT_1D subtypes, which play a crucial role in the vasoconstriction of cranial blood vessels and the inhibition of pro-inflammatory neuropeptide release. The unique characteristics of Rizatriptan N10-Oxide-d6 make it a valuable tool for understanding the behavior of triptans in biological systems.

Rizatriptan N10-Oxide-d6

1261392-57-7: Rizatriptan N10-Oxide-d6 is a deuterated derivative of rizatriptan, a medication primarily used for the acute treatment of migraine attacks. The "N10-Oxide" designation indicates that the nitrogen atom in the 10 position of the rizatriptan structure has been oxidized, which can influence the compound's pharmacological properties. The "d6" suffix signifies that the compound is deuterated, meaning that six hydrogen atoms have been replaced with deuterium, a stable isotope of hydrogen. This modification can enhance the compound's stability and alter its metabolic pathways, making it useful in research applications, particularly in pharmacokinetics and drug metabolism studies. Rizatriptan itself is a selective agonist for serotonin receptors, specifically the 5-HT_1B and 5-HT_1D subtypes, which play a crucial role in the vasoconstriction of cranial blood vessels and the inhibition of pro-inflammatory neuropeptide release. The unique characteristics of Rizatriptan N10-Oxide-d6 make it a valuable tool for understanding the behavior of triptans in biological systems.

CAS 1261392-57-7

Rizatriptan N10-Oxide-d6

Rizatriptan EP Impurity H N10-d6 (Rizatriptan N10-Oxide-d6)

Ref: 4Z-R-1247