CAS 1261393-15-0

Apixaban-13C-d3

CAS: 1261393-15-0

Formula: C₂₄₁₃CH₂₂D₃N₅O₄

Color and Shape: White To Off-White Solid

Molecular weight: 463.52

Ref: 4Z-A-10202

Apixaban 13C,d3

CAS: 1261393-15-0

Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa

Formula: C₂₅H₂₅N₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 463.51

Ref: TM-T10349

Apixaban-13C, d3

Controlled Product

CAS: 1261393-15-0

Applications Apixaban-13C, d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);

Formula: C₂₄₁₃CH₂₂D₃N₅O₄

Color and Shape: Off White

Molecular weight: 463.51

Ref: TR-A726702

Apixaban-13C, d3

Controlled Product

CAS: 1261393-15-0

Apixaban-13C, d3 is a chromatographic and spectrometric standard that is used in the linkage of pharmaceuticals. It is a bioavailable inhibitor that prevents coagulation by inhibiting the activity of thrombin. Apixaban-13C, d3 has a low level of toxicity and can be administered orally or intravenously. The pharmacokinetic profile for this compound has been determined using ammonium formate as an internal standard. Calibration was performed using mass spectrometry to confirm the molecular weight at 274.2 amu.

Formula: C₂₅H₂₂D₃N₅O₄

Purity: Min. 95%

Molecular weight: 463.51 g/mol

Ref: 3D-LAC39315