CAS 1262036-50-9

N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide

Description:

N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide is a complex organic compound characterized by its unique structural features, including a fused bicyclic system and multiple functional groups. The presence of a fluorine atom in both the phenyl and pyridine rings enhances its lipophilicity and may influence its biological activity. The thiazine moiety contributes to its potential pharmacological properties, as compounds containing such structures are often investigated for their therapeutic effects. The amino group suggests potential for hydrogen bonding, which can enhance solubility and interaction with biological targets. This compound's specific stereochemistry, indicated by the (4aS,7aS) configuration, is crucial for its biological activity, as stereoisomers can exhibit significantly different properties. Overall, this substance may be of interest in medicinal chemistry, particularly in the development of novel pharmaceuticals targeting specific biological pathways. Further studies would be necessary to elucidate its full range of properties and potential applications.

Formula: C₁₈H₁₆F₂N₄O₂S

InChI: InChI=1S/C18H16F2N4O2S/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18/h1-6,10H,7-9H2,(H2,21,24)(H,23,25)/t10-,18-/m0/s1

InChI key: InChIKey=NIDRNVHMMDAAIK-YPMLDQLKSA-N

SMILES: FC=1C([C@@]23[C@@](COC2)(CSC(N)=N3)[H])=CC(NC(=O)C4=CC=C(F)C=N4)=CC1

Synonyms:

• 2-Pyridinecarboxamide, N-[3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-
• Ly 2886721
• N-(3-((4As,7as)-2-amino-4A,5,7,7A-tetrahydro-4H-furo[3,4-D][1,3]thiazin-7A-yl)-4-fluorophenyl)-5-fluoropicolinamide
• N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
• VTP 37948
• BI 1181181

LY2886721

CAS: 1262036-50-9

Formula: C₁₈H₁₆F₂N₄O₂S

Purity: 98%

Molecular weight: 390.4070

Ref: IN-DA009CCW

LY2886721

CAS: 1262036-50-9

LY2886721

Purity: ≥98%

Molecular weight: 390.41g/mol

Ref: 54-BUP10256

LY2886721

CAS: 1262036-50-9

LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.

Formula: C₁₈H₁₆F₂N₄O₂S

Purity: 99% - 99.75%

Color and Shape: Solid

Molecular weight: 390.41

Ref: TM-T6058

LY 2886721 - Bio-X ™

CAS: 1262036-50-9

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₈H₁₆F₂N₄O₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 390.41 g/mol

Ref: 3D-BL300094

LY 2886721

CAS: 1262036-50-9

Inhibitor of BACE1 protease

Formula: C₁₈H₁₆F₂N₄O₂S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 390.41 g/mol

Ref: 3D-FL103714