CAS 1262036-50-9: N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide

Description: N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide is a complex organic compound characterized by its unique structural features, including a fused bicyclic system and multiple functional groups. The presence of a fluorine atom in both the phenyl and pyridine rings enhances its lipophilicity and may influence its biological activity. The thiazine moiety contributes to its potential pharmacological properties, as compounds containing such structures are often investigated for their therapeutic effects. The amino group suggests potential for hydrogen bonding, which can enhance solubility and interaction with biological targets. This compound's specific stereochemistry, indicated by the (4aS,7aS) configuration, is crucial for its biological activity, as stereoisomers can exhibit significantly different properties. Overall, this substance may be of interest in medicinal chemistry, particularly in the development of novel pharmaceuticals targeting specific biological pathways. Further studies would be necessary to elucidate its full range of properties and potential applications.

Formula: C₁₈H₁₆F₂N₄O₂S

InChI: InChI=1S/C18H16F2N4O2S/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18/h1-6,10H,7-9H2,(H2,21,24)(H,23,25)/t10-,18-/m0/s1

InChI key: InChIKey=NIDRNVHMMDAAIK-YPMLDQLKSA-N

SMILES: O=C(NC1=CC=C(F)C(=C1)C23N=C(SCC3COC2)N)C4=NC=C(F)C=C4

Synonyms:

• 2-Pyridinecarboxamide, N-[3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-
• Ly 2886721
• N-(3-((4As,7as)-2-amino-4A,5,7,7A-tetrahydro-4H-furo[3,4-D][1,3]thiazin-7A-yl)-4-fluorophenyl)-5-fluoropicolinamide
• N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
• VTP 37948
• BI 1181181

LY2886721

CAS: 1262036-50-9

• Formula: C₁₈H₁₆F₂N₄O₂S
• Purity: 98%
• Molecular weight: 390.407

LY2886721

CAS: 1262036-50-9

• Purity: 99.45%
• Molecular weight: 390.41g/mol

LY2886721

CAS: 1262036-50-9

LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.

• Formula: C₁₈H₁₆F₂N₄O₂S
• Purity: 99% - 99.94%
• Color and Shape: Solid
• Molecular weight: 390.41

LY 2886721 - Bio-X ™

CAS: 1262036-50-9

This product is part of our Bio-X ™ Range. These products are aimed at life …

• Formula: C₁₈H₁₆F₂N₄O₂S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 390.41 g/mol

LY 2886721

CAS: 1262036-50-9

Inhibitor of BACE1 protease

• Formula: C₁₈H₁₆F₂N₄O₂S
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 390.41 g/mol