CAS 1262041-49-5

ASK1-IN-1

CAS: 1262041-49-5

Formula: C₂₃H₂₁N₇O

Purity: 98%

Color and Shape: Solid

Molecular weight: 411.4591

Ref: IN-DA01DQAQ

GS-444217

CAS: 1262041-49-5

GS-444217

Purity: ≥98%

Molecular weight: 411.46g/mol

Ref: 54-BUP04093

ASK1-IN-1

CAS: 1262041-49-5

ASK1-IN-1

Purity: 99%

Color and Shape: Solid

Molecular weight: 411.46g/mol

Ref: 54-BISN0037

GS-444217

CAS: 1262041-49-5

GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).

Formula: C₂₃H₂₁N₇O

Purity: 99.08%

Color and Shape: Solid

Molecular weight: 411.46

Ref: TM-T5190

ASK1-IN-1

CAS: 1262041-49-5

ASK1-IN-1 is an activated form of a naturally occurring protein kinase, ASK1. It has been shown to be effective in reversing ventricular dysfunction and reducing nephropathy in a rat model of apical hypertensive nephrosclerosis. ASK1-IN-1 was also found to activate the mitochondrial membrane potential and increase growth factor production in cultured cells, which may contribute to its protective effects. More research is needed to determine the efficacy of ASK1-IN-1 for the treatment of diabetic retinopathy or other disorders.

Formula: C₂₃H₂₁N₇O

Purity: Min. 95%

Molecular weight: 411.46 g/mol

Ref: 3D-MAC04149