CAS 1262133-66-3

2'-O-(5'-Deoxy-beta-D-ribofuranosyl) Capecitabine

Description:

2'-O-(5'-Deoxy-beta-D-ribofuranosyl) Capecitabine is a nucleoside analog and a prodrug of the chemotherapeutic agent capecitabine, which is primarily used in the treatment of various cancers, including breast and colorectal cancer. This compound features a ribofuranosyl sugar moiety, which is modified at the 2' position, enhancing its stability and bioavailability. The presence of the 5'-deoxy modification contributes to its pharmacological properties, allowing for selective activation in tumor tissues. The mechanism of action involves the conversion to 5-fluorouracil (5-FU) in the body, which interferes with DNA synthesis and ultimately inhibits cancer cell proliferation. The compound is characterized by its relatively low toxicity to normal cells compared to traditional chemotherapeutics, making it a valuable option in cancer therapy. Its chemical structure includes specific functional groups that facilitate its interaction with enzymes involved in nucleotide metabolism. Overall, 2'-O-(5'-Deoxy-beta-D-ribofuranosyl) Capecitabine exemplifies the advancements in targeted cancer treatment through the design of prodrugs that enhance therapeutic efficacy while minimizing side effects.

Formula: C₂₀H₃₀FN₃O₉

Synonyms:

• 5'-Deoxy-2'-O-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-N-[(pentyloxy)carbonyl]cytidine
• [1-[5'-Deoxy-2-O-(5'-deoxy-β-D-ribofuranosyl)-β-D-ribofuranosyl]-5-fluoro-2-oxo-1,2-dihydropyriMidin-4-yl]carbaMic Acid Pentyl Ester
• 2'-O-(5'-Deoxy-β-D-ribofuranosyl) Capecitabine
• 2'-(5'-Deoxy-Beta-D-ribofuranoyl) Capecitabine
• Capecitabine impurity 2/Capecitabine USP Impurity H/Capecitabine 2-O-BDR Impurity
• 2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
• Capecitabine 2-O-BDR Impurity (USP)
• Capecitabine-related impurities G
• 2'-O-(5'-Deoxy-beta-D-ribofuranosyl) Capecitabine
• [1-[5'-Deoxy-2-O-(5'-deoxy-β-D-ribofuranosyl)-β-D-ribofuranosyl] -5-fluoro-2-oxo-1,2-dihydropyriMidin-4-yl] carbamic acid pentyl ester
• Capecitabine USP Impurity H
• Capecitabine 2-O-BDR Imp
• Capecitabin iMpurity H
• Capecitabine Impurity H(USP)
• Capecitabine Related Compound H
• Cytidine, 5'-deoxy-2'-O-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-N-[(pentyloxy)carbonyl]-
• Capecitabine impurity 2/Capecitabine USP Impurity H/Capecitabine 2-O-BDR Impurity/2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine
• Capecitabine USP IMp.H
• 2'-O-(5'-Deoxy-2,3-diacetyl-β-D-ribofuranosyl) Capecitabine 3-Benzoate
• Capecitabine 2-O-DR Impurity
• Capecitabine Impurity L
• Capecitabine-6

2'-O-(5-deoxy-β-D-ribofuranosyl) Capecitabine ([1-[5-Deoxy-2-O-(5-deoxy-β-D-ribofuranosyl)-β-D-ribofuranosyl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]-carbamic acid pentyl ester)

CAS: 1262133-66-3

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₂₀H₃₀FN₃O₉

Color and Shape: Off-White Light Green Solid

Molecular weight: 475.19661

Ref: 45-1A06670

2’-O-(5’-Deoxy-b-D-ribofuranosyl) Capecitabine

CAS: 1262133-66-3

Formula: C₂₀H₃₀FN₃O₉

Purity: 95%

Color and Shape: Solid

Molecular weight: 475.4653

Ref: IN-DA009F4G

Capecitabine Impurity 39

CAS: 1262133-66-3

Formula: C₂₀H₃₀FN₃O₉

Color and Shape: Off-White Solid

Molecular weight: 475.48

Ref: 4Z-C-359

2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine-d11

Controlled Product

CAS: 1262133-66-3

Applications Labelled Capecitabine (C175650) impurity.

Formula: C₂₀D₁₁H₁₉FN₃O₉

Color and Shape: Neat

Molecular weight: 486.533

Ref: TR-D251002

2’-O-(5’-Deoxy-β-D-ribofuranosyl) Capecitabine

Controlled Product

CAS: 1262133-66-3

Impurity Capecitabine 2-O-BDR Impurity (USP)
Stability Hygroscopic
Applications Capecitabine (C175650) impurity. Capecitabine 2-O-BDR Impurity (USP).

Formula: C₂₀H₃₀FN₃O₉

Color and Shape: Neat

Molecular weight: 475.47

Ref: TR-D251000

Capecitabine 2-O-BDR Impurity

CAS: 1262133-66-3

Formula: C₂₀H₃₀FN₃O₉

Molecular weight: 475.47

Ref: ST-EA-CP-C52009

2™-O-(5™-Deoxy-²-D-ribofuranosyl) Capecitabine-d11

CAS: 1262133-66-3

Please enquire for more information about 2™-O-(5™-Deoxy-²-D-ribofuranosyl) Capecitabine-d11 including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₀H₁₉D₁₁FN₃O₉

Purity: Min. 95%

Molecular weight: 486.53 g/mol

Ref: 3D-MAC13366