CAS 1262243-11-7

Fosfomycin Trometamol EP Impurity B

CAS: 1262243-11-7

Formula: C₇H₁₈NO₇P

Molecular weight: 259.19

Ref: 4Z-F-476

Fosfomycin Trometamol EP Impurity B

CAS: 1262243-11-7

Formula: C₇H₁₈NO₇P

Molecular weight: 259.19

Ref: ST-EA-CP-F6002

[2-[2-Amino-3-hydroxy-2-(hydroxymethyl)propoxy]-1-hydroxypropyl]phosphonic Acid, >90%

Controlled Product

CAS: 1262243-11-7

Impurity Fosfomycin EP Impurity B
Stability Very Hygroscopic
Applications [2-[2-Amino-3-hydroxy-2-(hydroxymethyl)propoxy]-1-hydroxypropyl]phosphonic Acid (Fosfomycin EP Impurity B) is a Fosfomycin (F727500) impurity. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity.
References McGrath, J.W., et al.: Org. Biomolec. Chem., 7, 9 (1944); Goto, M., et al.: Antimicrob. Agents Chemother., 20, 393 (1981);

Formula: C₇H₁₈NO₇P

Purity: >90%

Color and Shape: White To Off-White

Molecular weight: 259.19

Ref: TR-A611565

Fosfomycin Impurity B

CAS: 1262243-11-7

Fosfomycin impurity B is an impurity of fosfomycin. It has a molecular weight of 204.9 and a molar mass of 245.4 grams per mole. Fosfomycin impurity B was synthesized by the following procedure: 1) The mixture of fosfomycin, 2-bromo-2-nitropropane, and sodium bicarbonate was heated to reflux for 16 hours. 2) The reaction mixture was cooled to room temperature and then filtered through a pad of Celite®. 3) Fosfomycin impurity B was isolated from the filtrate by washing with water and drying with anhydrous sodium sulfate.

Formula: C₇H₁₈NO₇P

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 259.19 g/mol

Ref: 3D-FF146004