CAS 1262440-25-4

Dezapelisib

CAS: 1262440-25-4

Dezapelisib is a potent, selective small molecule activator of the human epidermal growth factor receptor 2 (HER2) receptor. It is an antibody-like small molecule that binds to the extracellular domain of the HER2 receptor and activates its signaling pathway. Dezapelisib has been shown to inhibit tumor growth in several different xenograft models, including mouse models of breast cancer and ovarian cancer, as well as in a mouse model of lung cancer. In preclinical studies, dezapelisib has also demonstrated activity against other tumor types including colon cancer and pancreatic cancer. As such, dezapelisib may be useful for treating patients with cancers that have HER2 overexpression or amplification.

Formula: C₂₀H₁₆FN₇OS

Purity: Min. 95%

Molecular weight: 421.5 g/mol

Ref: 3D-MAC44025

Dezapelisib

CAS: 1262440-25-4

Dezapelisib, an oral delta PI3K inhibitor, blocks PIP3 production and PI3K/AKT pathway, hindering tumor cell growth and survival.

Formula: C₂₀H₁₆FN₇OS

Color and Shape: Solid

Molecular weight: 421.45

Ref: TM-T27157