CAS 1262780-97-1

Etelcalcetide

Description:

Etelcalcetide is a synthetic peptide that functions as a calcimimetic agent, primarily used in the management of secondary hyperparathyroidism in patients with chronic kidney disease undergoing dialysis. Its mechanism of action involves the modulation of calcium-sensing receptors, leading to a decrease in parathyroid hormone (PTH) secretion. This helps to regulate calcium and phosphate metabolism, thereby reducing the risk of bone disease associated with elevated PTH levels. Etelcalcetide is administered via intravenous injection and has a longer half-life compared to other calcimimetics, allowing for less frequent dosing. The substance is characterized by its specific amino acid sequence, which contributes to its biological activity, and it is typically formulated as a sterile solution for injection. As with any medication, potential side effects may include nausea, vomiting, and hypocalcemia, necessitating careful monitoring of calcium levels during treatment. Overall, etelcalcetide represents an important therapeutic option for managing mineral and bone disorders in patients with renal impairment.

Etelcalcetide Pentatrifluoroacetate

CAS: 1262780-97-1, 1334237-71-6

Formula: C₃₈H₇₃N₂₁O₁₀S₂·5C₂HF₃O₂

Molecular weight: 1048.26 5*114.02

Ref: 4Z-PE-192002

Etelcalcetide

CAS: 1262780-97-1

Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.

Formula: C₃₈H₇₃N₂₁O₁₀S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1048.26

Ref: TM-TP1235

Etelcalcetide

CAS: 1262780-97-1

Formula: C₃₈H₇₃N₂₁O₁₀S₂

Molecular weight: 1048.26

Ref: 4Z-PE-192001

Etelcalcetide

CAS: 1262780-97-1

Agonist of calcium sensing receptor CASR; calcimimetic agent

Formula: C₃₈H₇₃N₂₁O₁₀S₂

Purity: Min. 95%

Molecular weight: 1,048.25 g/mol

Ref: 3D-FE162097