CAS 1263-79-2

(-)-Tetrandrine

Description:

(-)-Tetrandrine is a bisbenzylisoquinoline alkaloid primarily derived from the Chinese herb Stephania tetrandra. It is known for its distinctive structural features, which include two benzylisoquinoline units linked by a carbon chain. This compound exhibits a range of biological activities, including anti-inflammatory, anti-cancer, and anti-arrhythmic properties. Its mechanism of action is thought to involve the modulation of calcium channels and various signaling pathways, contributing to its therapeutic potential. (-)-Tetrandrine is also recognized for its ability to inhibit certain types of cell proliferation and induce apoptosis in cancer cells. Additionally, it has been studied for its effects on cardiovascular health, particularly in the context of hypertension. The substance is typically found in a crystalline form and is soluble in organic solvents, but its solubility in water is limited. Due to its pharmacological properties, (-)-Tetrandrine has garnered interest in both traditional medicine and modern pharmacology, although further research is necessary to fully elucidate its mechanisms and potential clinical applications.

Formula: C₃₈H₄₂N₂O₆

InChI: InChI=1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m1/s1

InChI key: InChIKey=WVTKBKWTSCPRNU-LOYHVIPDSA-N

SMILES: O(C)C1=C2C=3[C@@](CC=4C=C(C(OC)=CC4)OC=5C=CC(C[C@@]6(C7=CC(O2)=C(OC)C=C7CCN6C)[H])=CC5)(N(C)CCC3C=C1OC)[H]

Synonyms:

• Berbaman, 6,6′,7,12-tetramethoxy-2,2′-dimethyl-, (1′β)-
• 16H-1,24:6,9-Dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, 3,4,4a,5,16a,17,18,19-octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-, (4aR,16aR)-
• (4aR,16aR)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline
• (-)-Tetrandrine
• Pheanthine

Pheanthine

CAS: 1263-79-2

Pheanthine

Purity: ≥98%

Molecular weight: 622.75g/mol

Ref: 54-BUP00414

Pheanthine

CAS: 1263-79-2

Pheanthine is an extract of the fruit of Gyrocarpus jacquinii and shows induction of C/EBPα activity.

Formula: C₃₈H₄₂N₂O₆

Purity: 98.71%

Color and Shape: Solid

Molecular weight: 622.75

Ref: TM-T8417