
CAS 126300-89-8
:O-(Difluoromethyl)tyrosine
Description:
O-(Difluoromethyl)tyrosine is a synthetic analog of the amino acid tyrosine, characterized by the presence of a difluoromethyl group at the ortho position of the phenolic hydroxyl group. This modification can influence its biochemical properties, including its reactivity and interactions with enzymes and receptors. The difluoromethyl group enhances lipophilicity, potentially affecting the compound's bioavailability and cellular uptake. As a derivative of tyrosine, it retains the basic structure of an amino acid, featuring an amino group, a carboxylic acid group, and a side chain that includes the modified phenolic ring. This compound is of interest in biochemical research, particularly in studies related to protein synthesis, enzyme inhibition, and the development of pharmaceuticals targeting tyrosine-related pathways. Its unique fluorinated structure may also impart distinct pharmacological properties, making it a valuable tool in medicinal chemistry and drug design. Safety and handling considerations should be observed due to the presence of fluorine, which can pose specific health risks.
Formula:C10H11F2NO3
InChI:InChI=1S/C10H11F2NO3/c11-10(12)16-7-3-1-6(2-4-7)5-8(13)9(14)15/h1-4,8,10H,5,13H2,(H,14,15)
InChI key:InChIKey=ITFQXKAULLPDSW-UHFFFAOYSA-N
SMILES:C(C(C(O)=O)N)C1=CC=C(OC(F)F)C=C1
Synonyms:- DL-Tyrosine, O-(difluoromethyl)-
- Tyrosine, O-(difluoromethyl)-
- 2-Amino-3-[4-(difluoromethoxy)phenyl]propanoic acid
- O-(Difluoromethyl)tyrosine
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