CAS 1263077-74-2

AM-211 sodium

CAS: 1263077-74-2

The peptide AM-211 is a potent activator of the TRPV1 receptor, which is expressed in sensory neurons. This receptor is activated by heat and capsaicin, and mediates pain sensation. AM-211 has been shown to inhibit voltage-gated sodium channels, which are involved in the generation of action potentials. It also binds to the extracellular domain of the Nogo receptor and blocks its interaction with its ligands. TRPV1 receptors have been implicated in various diseases such as chronic pain, inflammatory bowel disease, diabetes mellitus type 2, osteoarthritis and rheumatoid arthritis.

Formula: C₂₇H₂₆F₃N₂NaO₄

Purity: Min. 95%

Molecular weight: 522.5 g/mol

Ref: 3D-NAC07774

AM-211 sodium

CAS: 1263077-74-2

AM-211 sodium: potent DP2 receptor antagonist, active against allergic inflammation, selective, and orally bioavailable in rats and dogs.

Formula: C₂₇H₂₆F₃N₂NaO₄

Color and Shape: Solid

Molecular weight: 522.5

Ref: TM-T71088