CAS 1263373-43-8

4-((5'-chloro-2'-((1R,4r)-4-((R)-1-methoxypropan-2-ylamino)cyclohexylamino)-2,4'-bipyridin-6-ylamino)methyl)tetrahydro-2H-pyran-4-carbonitrile

Description:

The chemical substance with the name "4-((5'-chloro-2'-((1R,4r)-4-((R)-1-methoxypropan-2-ylamino)cyclohexylamino)-2,4'-bipyridin-6-ylamino)methyl)tetrahydro-2H-pyran-4-carbonitrile" and CAS number 1263373-43-8 is a complex organic compound characterized by multiple functional groups and a multi-cyclic structure. It features a tetrahydropyran ring, which contributes to its cyclic nature, and a bipyridine moiety that may impart specific electronic properties. The presence of a chloro substituent suggests potential reactivity, while the carbonitrile group indicates the presence of a nitrile functional group, which can influence the compound's polarity and solubility. The compound also contains amino groups, which may enhance its ability to form hydrogen bonds and interact with biological targets. Overall, this substance is likely to exhibit unique pharmacological properties, making it of interest in medicinal chemistry and drug development. Its structural complexity suggests potential applications in various fields, including pharmaceuticals and agrochemicals.

NVP-2

CAS: 1263373-43-8

NVP-2 selectively inhibits CDK9 (IC50: 0.514 nM), prompts apoptosis, and affects other CDKs (IC50: 0.584-0.706 μM).

Formula: C₂₇H₃₇ClN₆O₂

Purity: 99.13%

Color and Shape: Solid

Molecular weight: 513.07

Ref: TM-T16363

NVP-2

CAS: 1263373-43-8

NVP-2

Purity: ≥98%

Molecular weight: 513.07g/mol

Ref: 54-BUP05435

NVP-2

CAS: 1263373-43-8

Purity: 97%

Molecular weight: 513.08

Ref: 10-F979416

NVP 2

CAS: 1263373-43-8

NVP-2 is a potent inhibitor of HIV protease. It has been shown to inhibit the proteolytic cleavage of human immunodeficiency virus (HIV) polyproteins, which are required for viral replication. NVP-2 also inhibits the binding of melanoma tumor cells with human immunodeficiency virus type 1 (HIV-1). NVP-2 is soluble in water and can be used as a coating on polyvinyl chloride (PVC) to prevent radiation induced damage to human skin cells. NVP-2 binds to messenger RNA, preventing protein synthesis and gene expression in cancer cells. Hydrogen bonds between NVP-2 and DNA bases are important for its ability to inhibit HIV protease.

Formula: C₂₇H₃₇ClN₆O₂

Purity: Min. 95%

Molecular weight: 513.07 g/mol

Ref: 3D-NAC37343