CAS 1264-57-9

Decanoyl CoA

Description:

Decanoyl CoA, also known as decanoyl coenzyme A, is a fatty acyl-CoA derivative characterized by its role in lipid metabolism. It is a thioester formed from decanoic acid and coenzyme A, featuring a long hydrophobic carbon chain, which contributes to its amphipathic nature. This compound plays a crucial role in the synthesis and degradation of fatty acids, serving as an important intermediate in various metabolic pathways, including β-oxidation and fatty acid elongation. Decanoyl CoA is involved in the regulation of energy metabolism and is essential for the biosynthesis of complex lipids. Its structure includes a decanoyl group linked to the coenzyme A moiety, which contains a nucleotide and a pantothenic acid derivative. The presence of the thiol group allows for the formation of thioester bonds, facilitating the transfer of acyl groups in metabolic reactions. Due to its involvement in metabolic processes, decanoyl CoA is significant in both cellular energy production and the synthesis of bioactive lipids.

Formula: C₃₁H₅₄N₇O₁₇P₃S

InChI: InChI=1S/C31H54N7O17P3S/c1-4-5-6-7-8-9-10-11-22(40)59-15-14-33-21(39)12-13-34-29(43)26(42)31(2,3)17-52-58(49,50)55-57(47,48)51-16-20-25(54-56(44,45)46)24(41)30(53-20)38-19-37-23-27(32)35-18-36-28(23)38/h18-20,24-26,30,41-42H,4-17H2,1-3H3,(H,33,39)(H,34,43)(H,47,48)(H,49,50)(H2,32,35,36)(H2,44,45,46)/t20-,24-,25-,26+,30-/m1/s1

InChI key: InChIKey=CNKJPHSEFDPYDB-HSJNEKGZSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(CCCCCCCCC)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Synonyms:

• Capryl CoA
• Capryl coenzyme A
• Coenzyme A, S-decanoate
• Decanoyl CoA
• Decanoyl coenzyme A
• N-decanoylcoenzyme A
• S-{(9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} decanethioate (non-preferred name)
• S-{1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} decanethioate (non-preferred name)
• n-Decanoyl-CoA

Decanoyl coenzyme A

CAS: 1264-57-9

Formula: C₃₁H₅₄N₇O₁₇P₃S

Purity: 90%

Color and Shape: Solid

Molecular weight: 921.7834

Ref: IN-DA000SQU

Decanoyl coenzymexa0A monohydrate

CAS: 1264-57-9

Formula: C₃₁H₅₄N₇O₁₇P₃S

Molecular weight: 939.80

Ref: 7W-GK3983

Decanoyl coenzyme A

CAS: 1264-57-9

Decanoyl coenzyme A (Decanoyl CoA) serves as a primer for the fatty acid elongation system in Mycobacterium smegmatis [1].

Formula: C₃₁H₅₄N₇O₁₇P₃S

Color and Shape: Solid

Molecular weight: 921.78

Ref: TM-T74115

Decanoyl Coenzyme A free acid

CAS: 1264-57-9

Formula: C31H54N7O17P3S

Purity: >95%

Color and Shape: Solid

Molecular weight: 921.79

Ref: 48-19-1000

Decanoyl coenzyme A Sodium

Controlled Product

CAS: 1264-57-9

Applications Decanoyl coenzyme A, free acid (CAS# 1264-57-9) is a useful research chemical compound.

Formula: C₃₁H₅₄N₇O₁₇P₃S·Na

Color and Shape: Neat

Molecular weight: 921.783

Ref: TR-D210950

Decanoyl coenzyme A, free acid

CAS: 1264-57-9

Decanoyl CoA, free acid, is a substrate of the enzyme fatty acid synthetase. This enzyme catalyzes the formation of long-chain fatty acids from acetyl-CoA and malonyl-CoA. The product decanoyl-CoA is then used in other metabolic pathways to synthesize acyl chains for phospholipids, triglycerides, and cholesterol. Decanoyl CoA has been shown to inhibit carnitine acyltransferase activity in rat liver microsomes. It also inhibits mitochondrial beta-oxidation by competing with carnitine at the level of the carnitine acyltransferase reaction. The expression plasmid pET21a was used to express the decanoyl CoA synthetase protein in Escherichia coli cells grown in LB medium with aminotransferase activity as a measure of decanoyl CoA synthetase activity. Decanoyl CoA

Formula: C₃₁H₅₄N₇O₁₇P₃S

Purity: Min. 95%

Molecular weight: 921.78 g/mol

Ref: 3D-ND47196