CAS 126451-47-6
:(S)-(+)-Manidipine
Description:
(S)-(+)-Manidipine is a calcium channel blocker primarily used in the treatment of hypertension. It belongs to the dihydropyridine class of compounds and is characterized by its chiral nature, with the (S)-enantiomer being the active form. The substance exhibits a high affinity for L-type calcium channels, leading to vasodilation and a subsequent reduction in blood pressure. Its chemical structure includes a dihydropyridine ring, which is essential for its pharmacological activity. (S)-(+)-Manidipine is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. The compound is known for its favorable side effect profile compared to other antihypertensives, making it a preferred choice in certain patient populations. Additionally, it may have protective effects on the cardiovascular system beyond blood pressure reduction. As with any medication, monitoring for potential interactions and side effects is essential during treatment.
Formula:C35H38N4O6
Synonyms:- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (4S)- (9CI)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[4-(diphenylmethyl)-1-piperazinyl]ethyl methyl ester, (S)-
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