CAS 1265917-14-3

S1RA (hydrochloride)

Description:

S1RA (hydrochloride) is a chemical compound that acts as a selective antagonist for the S1 receptor, which is involved in various physiological processes, including pain modulation and neuroprotection. This substance is characterized by its ability to inhibit the activity of the S1 receptor, potentially offering therapeutic benefits in conditions such as neuropathic pain and other neurological disorders. As a hydrochloride salt, S1RA is typically more soluble in water, enhancing its bioavailability for pharmacological applications. The compound's molecular structure includes specific functional groups that contribute to its receptor-binding properties. In research settings, S1RA (hydrochloride) is often utilized in studies to elucidate the role of the S1 receptor in various biological systems and to explore its potential as a drug candidate. Safety and handling precautions are essential, as with any chemical substance, to mitigate risks associated with exposure. Overall, S1RA (hydrochloride) represents a significant interest in pharmacological research due to its targeted action on the S1 receptor.

Formula: C₂₀H₂₄ClN₃O₂

Synonyms:

• S1RA (hydrochloride)
• E 52862 hydrochloride
• S1RA. HCL
• 4-(2-(5-methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy)ethyl)morpholine hydrochloride
• E-52862 hydrochloride
• 177303
• S1RA HCl (E-52862)
• 4-[2-[[5-Methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine hydrochloride (1:1)
• S1RA (E-52862) HCI
• E52862 hydrochloride
• E-52862 HYDROCHLORIDE;E52862 HYDROCHLORIDE;E 52862 HYDROCHLORIDE

S1RA (hydrochloride)

CAS: 1265917-14-3

Formula: C₂₀H₂₄ClN₃O₂

Purity: %

Color and Shape: Solid

Molecular weight: 373.8765

Ref: IN-DA009CEN

4-(2-((5-Methyl-1-(Naphthalen-2-Yl)-1H-Pyrazol-3-Yl)Oxy)Ethyl)Morpholine Hydrochloride

CAS: 1265917-14-3

4-(2-((5-Methyl-1-(Naphthalen-2-Yl)-1H-Pyrazol-3-Yl)Oxy)Ethyl)Morpholine Hydrochloride

Purity: 99%

Molecular weight: 373.88g/mol

Ref: 54-OR1024030

S1RA hydrochloride

CAS: 1265917-14-3

S1RA hydrochloride

Purity: ≥98%

Molecular weight: 373.87g/mol

Ref: 54-BUP09255

S1RA hydrochloride

CAS: 1265917-14-3

S1RA hydrochloride (E-52862 hydrochloride) is an effective and specific sigma-1 receptor(σ1R, Ki: 17 nM) antagonist, and has good selectivity against σ2R (Ki >

Formula: C₂₀H₂₄ClN₃O₂

Purity: 98% - 99.84%

Color and Shape: Solid

Molecular weight: 373.87

Ref: TM-T4229

S1RA hydrochloride

CAS: 1265917-14-3

S1RA hydrochloride is a selective antagonist targeting the sigma-1 receptor, which is a type of small molecule ligand. It is synthesized chemically, enabling precise modulation of its properties for experimental use. S1RA functions by selectively inhibiting the sigma-1 receptor, a chaperone protein involved in modulating ion channels and other receptors within the endoplasmic reticulum. This modulation plays a critical role in various cellular processes, including calcium signaling and cellular stress responses.

Formula: C₂₀H₂₃N₃O₂•HCl

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 373.88 g/mol

Ref: 3D-BS177543