CymitQuimica logo

CAS 126671-71-4

:

8-Hydroxyondansetron

Description:
8-Hydroxyondansetron is a chemical compound that is a derivative of ondansetron, which is primarily known as an antiemetic used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. The compound features a hydroxyl group at the 8-position of the indole ring, which may influence its pharmacological properties. It is characterized by its molecular structure that includes a benzamide moiety, contributing to its interaction with serotonin receptors, particularly the 5-HT3 receptor. This modification can potentially enhance its efficacy or alter its side effect profile compared to ondansetron. The compound is typically studied for its biological activity, including its potential effects on serotonin signaling and its role in various therapeutic applications. As with many pharmaceuticals, its solubility, stability, and bioavailability are critical factors that influence its effectiveness and safety in clinical settings. Overall, 8-Hydroxyondansetron represents an interesting area of research within medicinal chemistry, particularly in the context of antiemetic drug development.
Formula:C18H19N3O2
InChI:InChI=1S/C18H19N3O2/c1-11-19-8-9-21(11)10-12-6-7-14-16(18(12)23)13-4-3-5-15(22)17(13)20(14)2/h3-5,8-9,12,22H,6-7,10H2,1-2H3
InChI key:InChIKey=XVDKMEPUFIAQFH-UHFFFAOYSA-N
SMILES:O=C1C=2C=3C(N(C)C2CCC1CN4C(C)=NC=C4)=C(O)C=CC3
Synonyms:
  • 1,2,3,9-Tetrahydro-8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one
  • 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-
  • 8-Hydroxyondansetron
  • 8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one
  • Gr 90315
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 5 products.