Description:FMOC-ACPC-OH, or 9-fluorenylmethoxycarbonyl (FMOC)-L-α-amino-cyclopentanecarboxylic acid, is a chemical compound commonly used in peptide synthesis as a protecting group for amino acids. The FMOC group is known for its stability under basic conditions and can be easily removed under mild acidic conditions, making it advantageous in multi-step synthesis. The cyclopentanecarboxylic acid moiety introduces a unique cyclic structure that can influence the conformation and properties of peptides. FMOC-ACPC-OH is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its molecular structure contributes to its role in enhancing the stability and solubility of peptides during synthesis. Additionally, the compound is utilized in various research applications, particularly in the development of novel peptides and in studies related to drug design and delivery. As with many chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its use.
Fmoc-1-aminocyclopropane-1-carboxylic acid is a conformationally constrained analog of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid. It interacts with proteases and …
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