CAS 126727-04-6

Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

Description:

Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]- is a derivative of the amino acid phenylalanine, modified with a fluorenylmethoxycarbonyl (Fmoc) protecting group. This compound is commonly used in peptide synthesis as a protective group for the amino group of phenylalanine, facilitating the selective coupling of amino acids during solid-phase peptide synthesis. The Fmoc group is favored for its stability under basic conditions and ease of removal under mild acidic conditions, making it advantageous in synthetic chemistry. The presence of the fluorenyl group contributes to the compound's hydrophobic characteristics, influencing its solubility and interaction with other molecules. Additionally, the structure of this compound allows for potential applications in drug development and biochemistry, particularly in the design of peptides with specific biological activities. Overall, this compound exemplifies the importance of protecting groups in organic synthesis, enabling the construction of complex biomolecules with precision.

Formula: C₂₄H₂₁NO₄

Synonyms:

• 2-(9H-Fluoren-9-Ylmethoxycarbonylamino)-3-Phenyl-Propionic Acid
• Timtec-Bb Sbb001432
• Fmoc-DL-Phe-OH
• Fmoc-DL-phenylalanine
• N-Alpha-9-Fluorenylmethoxycarbonyl-Dl-Phenylalanine
• N-9-Fluorenylmethoxycarbonyl-DL-phenylalanine
• (9H-Fluoren-9-yl)MethOxy]Carbonyl DL-Phe-OH
• 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-phenylpropanoic acid
• N-α-(9-Fluorenylmethoxycarbonyl)-DL-phenylalanine
• N-FMOC-DL-phenylalanine

Fmoc-DL-phenylalanine

CAS: 126727-04-6

Formula: C₂₄H₂₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 387.4278

Ref: IN-DA000T5U

Fmoc-DL-Phe-OH

CAS: 126727-04-6

Fmoc-DL-Phe-OH

Purity: 98%

Ref: 54-OR1040013

2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-phenylpropanoic acid

CAS: 126727-04-6

2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-phenylpropanoic acid (FAHP) is a chiral, nonracemic optical probe that is used to measure the ratio of d-glutamine to l-glutamine in the brain. It has been shown to have a linear response over the range of endogenous levels and to have no effect on cerebrospinal fluid chloride concentration or osmolarity. FAHP binds to β-cyclodextrin and emits fluorescence when excited by light at a wavelength of 360 nm. This compound is stable in acidic solutions and can be injected into the body without degradation. It has also been shown that FAHP causes enantioseparation of racemic mixtures of d-(+)-glucose and d-(−)-glucose.

Formula: C₂₄H₂₁NO₄

Purity: Min. 95%

Molecular weight: 387.4 g/mol

Ref: 3D-BFA72704