The chemical substance "H-Leu-His-Leu-OH," with the CAS number 126828-33-9, is a peptide composed of three amino acids: leucine (Leu), histidine (His), and leucine (Leu) again, with a C-terminal hydroxyl group. This structure indicates that it is a dipeptide with a specific sequence that may influence its biological activity and properties. Peptides like this one can exhibit various characteristics, including solubility in water, potential bioactivity, and the ability to interact with biological receptors or enzymes. The presence of leucine, an aliphatic amino acid, contributes to hydrophobic interactions, while histidine, with its imidazole side chain, can participate in hydrogen bonding and metal ion coordination. The hydroxyl group at the C-terminus may enhance solubility and reactivity. Such peptides are often studied for their roles in biological systems, including signaling pathways and metabolic processes, and may have applications in pharmaceuticals or biotechnology.

H-Leu-His-Leu-OH

126828-33-9: The chemical substance "H-Leu-His-Leu-OH," with the CAS number 126828-33-9, is a peptide composed of three amino acids: leucine (Leu), histidine (His), and leucine (Leu) again, with a C-terminal hydroxyl group. This structure indicates that it is a dipeptide with a specific sequence that may influence its biological activity and properties. Peptides like this one can exhibit various characteristics, including solubility in water, potential bioactivity, and the ability to interact with biological receptors or enzymes. The presence of leucine, an aliphatic amino acid, contributes to hydrophobic interactions, while histidine, with its imidazole side chain, can participate in hydrogen bonding and metal ion coordination. The hydroxyl group at the C-terminus may enhance solubility and reactivity. Such peptides are often studied for their roles in biological systems, including signaling pathways and metabolic processes, and may have applications in pharmaceuticals or biotechnology.

<p>H-Leu-His-Leu-OH is a peptide fragment of human growth hormone. It is a stabilized, cleaved, and lyophilized form of the substance that is used as an additive in buffering solutions. It has been shown to be a potent inhibitor of the proteolytic enzymes cathepsin B, elastase, and chymotrypsin in vitro. The stability of this fragment can be attributed to its resistance to proteolysis by enzymes such as cathepsin's B, elastase, and chymotrypsin because it does not contain any free amino acid residues.</p>

CAS 126828-33-9

H-Leu-His-Leu-OH

H-Leu-His-Leu-OH

Ref: IN-DA000TBF

H-Leu-His-Leu-OH

Ref: 3D-FL109489