CAS 1268356-17-7

Nilotinib-d6

CAS: 1268356-17-7

Formula: C₂₈H₁₆D₆F₃N₇O

Color and Shape: Off-White Solid

Molecular weight: 535.56

Ref: 4Z-N-312

Nilotinib-d6

CAS: 1268356-17-7

Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.

Formula: C₂₈H₂₂F₃N₇O

Purity: 98%

Color and Shape: Solid

Molecular weight: 535.55

Ref: TM-T12224

Nilotinib-d6

Controlled Product

CAS: 1268356-17-7

Applications Nilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.
References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

Formula: C₂₈₂H₆H₁₆F₃N₇O

Color and Shape: Off-White To Light Beige

Molecular weight: 535.55

Ref: TR-N465303

Nilotinib-d6

CAS: 1268356-17-7

Nilotinib-d6 is a drug that binds to the Abl kinase, which is involved in the regulation of cell division and growth. This compound has been shown to have high specificity for the ABL kinase, with a concentration range of 0.01-1 μM. The reagent is extracted from organic solvents and then purified by an isotope dilution method. It is used as a calibration standard for drug concentration or detection methods such as liquid chromatography/mass spectrometry (LC/MS) or LC/MS/MS. Samples are collected from blood and analyzed using LC/MS or LC/MS/MS.

Formula: C₂₈H₂₂F₃N₇O

Purity: Min. 95%

Molecular weight: 535.6 g/mol

Ref: 3D-TAC35617