CAS 126844-81-3

nagstatin

Description:

Nagstatin, identified by its CAS number 126844-81-3, is a chemical compound that belongs to the class of natural products known as polyketides. It is primarily recognized for its role as a potent inhibitor of certain enzymes, particularly those involved in the biosynthesis of complex carbohydrates. Nagstatin exhibits antimicrobial properties, making it of interest in pharmaceutical research, particularly in the development of new antibiotics. The compound is derived from microbial sources, which is common for many polyketides, and its structure features a complex arrangement of carbon, hydrogen, and oxygen atoms. The specific stereochemistry and functional groups present in nagstatin contribute to its biological activity and interaction with target enzymes. Research into nagstatin continues to explore its potential therapeutic applications, as well as its mechanism of action and efficacy against various pathogens. Overall, nagstatin represents a significant area of study within the field of medicinal chemistry and natural product research.

Formula: C₁₂H₁₇N₃O₆

InChI: InChI=1/C12H17N3O6/c1-5(17)14-9-11(21)10(20)7(4-16)15-6(2-8(18)19)3-13-12(9)15/h3,7,9-11,16,20-21H,2,4H2,1H3,(H,14,17)(H,18,19)

Synonyms:

• Nagstatine
• Imidazo(1,2-alpha)pyridine-3-acetic acid, 5,6,7,8-tetrahydro-8-(acetylamino)-6,7-dihydroxy-5-(hydroxymethyl)-
• Imidazo(1,2-a)pyridine-3-acetic acid, 8-(acetylamino)-5,6,7,8-tetrahydro-6,7-dihydroxy-5-(hydroxymethyl)-
• [8-(acetylamino)-6,7-dihydroxy-5-(hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-3-yl]acetic acid
• Nagstatin
• Imidazo[1,2-a]pyridine-2-acetic acid, 8-(acetylamino)-5,6,7,8-tetrahydro-6,7-dihydroxy-5-(hydroxymethyl)-, (5R,6S,7R,8S)-

Nagstatin

CAS: 126844-81-3

Nagstatin is an inhibitor of N-acetyl-beta-D-glucosaminidase and is produced by Streptomyces amakusaensis MG846-fF3.

Formula: C₁₂H₁₇N₃O₆

Color and Shape: Solid

Molecular weight: 299.28

Ref: TM-T71081