Angiotensin III, a peptide hormone, is a significant component of the renin-angiotensin system, which plays a crucial role in regulating blood pressure and fluid balance in humans. It is derived from angiotensin II through the action of aminopeptidases and is known for its vasoconstrictive properties, although it is less potent than angiotensin II. The chemical structure of angiotensin III consists of a sequence of amino acids, specifically a heptapeptide, which influences its biological activity and receptor binding. It primarily interacts with the angiotensin II type 1 receptor (AT1R), contributing to various physiological effects, including the stimulation of aldosterone secretion and modulation of renal function. Angiotensin III is also involved in the pathophysiology of hypertension and cardiovascular diseases. Its CAS number, 12687-51-3, uniquely identifies this compound in chemical databases, facilitating research and clinical applications. Understanding its characteristics is essential for developing therapeutic strategies targeting the renin-angiotensin system in various health conditions.

Angiotensin III, Human

12687-51-3: Angiotensin III, a peptide hormone, is a significant component of the renin-angiotensin system, which plays a crucial role in regulating blood pressure and fluid balance in humans. It is derived from angiotensin II through the action of aminopeptidases and is known for its vasoconstrictive properties, although it is less potent than angiotensin II. The chemical structure of angiotensin III consists of a sequence of amino acids, specifically a heptapeptide, which influences its biological activity and receptor binding. It primarily interacts with the angiotensin II type 1 receptor (AT1R), contributing to various physiological effects, including the stimulation of aldosterone secretion and modulation of renal function. Angiotensin III is also involved in the pathophysiology of hypertension and cardiovascular diseases. Its CAS number, 12687-51-3, uniquely identifies this compound in chemical databases, facilitating research and clinical applications. Understanding its characteristics is essential for developing therapeutic strategies targeting the renin-angiotensin system in various health conditions.

Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor.

CAS 12687-51-3

Angiotensin III, Human

Angiotensin III

Ref: TM-T10322