CAS 126954-66-3

2,5-dichloronicotinonitrile

Description:

2,5-Dichloronicotinonitrile is a chemical compound characterized by its structure, which includes a pyridine ring substituted with two chlorine atoms and a nitrile group. This compound is typically a solid at room temperature and is known for its potential applications in pharmaceuticals and agrochemicals due to its biological activity. The presence of the nitrile group contributes to its reactivity, making it a useful intermediate in organic synthesis. The chlorine substituents can influence the compound's polarity and solubility, affecting its interaction with biological systems. Additionally, 2,5-dichloronicotinonitrile may exhibit specific toxicological properties, necessitating careful handling and storage. Its synthesis often involves chlorination and subsequent reactions to introduce the nitrile functionality. As with many halogenated compounds, it is important to consider environmental and health impacts, including potential persistence and bioaccumulation. Overall, 2,5-dichloronicotinonitrile is a compound of interest in various fields, particularly in the development of new chemical entities.

Formula: C₆H₂N₂Cl₂

InChI: InChI=1S/C6H2Cl2N2/c7-5-1-4(2-9)6(8)10-3-5/h1,3H

SMILES: c1c(C#N)c(Cl)ncc1Cl

Synonyms:

• 2,5-Dichloro-3-cyanopyridine
• 2,5-Dichloro-3-pyridinecarbonitrile
• 2,5-Dichloropyridine-3-carbonitrile
• 3-Pyridinecarbonitrile, 2,5-dichloro-
• T6Nj Bg Ccn Eg

3-Pyridinecarbonitrile, 2,5-dichloro-

CAS: 126954-66-3

Formula: C₆H₂Cl₂N₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 172.9995

Ref: IN-DA000WH5

2,5-Dichloronicotinonitrile

CAS: 126954-66-3

2,5-Dichloronicotinonitrile

Formula: C₆H₂Cl₂N₂

Purity: 98%

Color and Shape: Powder

Molecular weight: 173.00g/mol

Ref: 54-OR61381

2,5-Dichloronicotinonitrile

CAS: 126954-66-3

Formula: C₆H₂Cl₂N₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 173

Ref: 10-F239963

2,5-Dichloronicotinonitrile

CAS: 126954-66-3

2,5-Dichloronicotinonitrile is a phosphoinositide analog that has been shown to have cytotoxic effects in cancer cells. It binds to the phosphate groups on the cell membrane and inhibits the synthesis of phosphatidylinositol-3,4,5-trisphosphate (PIP3). This prevents the activation of Akt, which is a protein involved in cell survival and proliferation. The molecular modelling study showed that 2,5-Dichloronicotinonitrile can inhibit cancer cell proliferation at low nanomolar concentrations.

Formula: C₆H₂Cl₂N₂

Purity: Min. 95%

Molecular weight: 173 g/mol

Ref: 3D-BFA95466