CAS 12698-55-4
:Dolichyl phosphate
Description:
Dolichyl phosphate is a lipid molecule characterized by its long-chain polyisoprenoid structure, which is derived from dolichol. It plays a crucial role in the glycosylation process within cells, serving as a carrier for sugar moieties during the synthesis of glycoproteins and glycolipids. The phosphate group in dolichyl phosphate contributes to its amphipathic nature, allowing it to interact with both hydrophilic and hydrophobic environments, which is essential for its function in membrane dynamics and cellular processes. This compound is primarily found in the endoplasmic reticulum and is involved in the assembly of oligosaccharides that are transferred to nascent polypeptides. Additionally, dolichyl phosphate is implicated in various biological processes, including protein folding and quality control. Its dysregulation has been associated with certain diseases, highlighting its importance in cellular metabolism and function. Overall, dolichyl phosphate is a vital component in the post-translational modification of proteins, influencing their stability and activity within the cell.
Formula:H3O4P·Unspecified
InChI:InChI=1/C25H45O4P/c1-21(2)11-7-12-22(3)13-8-14-23(4)15-9-16-24(5)17-10-18-25(6)19-20-29-30(26,27)28/h11,13,15,17,25H,7-10,12,14,16,18-20H2,1-6H3,(H2,26,27,28)/b22-13+,23-15+,24-17-
Synonyms:- Dolichol monophosphate
- Dolichol phosphate
- Dolichol, dihydrogen phosphate
- Dolicholmonophosphate
- Dolichyl monophosphate
- Dolichyl phosphate
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