CAS 127-07-1: Hydroxyurea

Description: Hydroxyurea, with the CAS number 127-07-1, is a chemical compound that serves as an antineoplastic agent, primarily used in the treatment of certain cancers, such as chronic myeloid leukemia and head and neck cancers, as well as in managing sickle cell disease. It is a white, crystalline solid that is soluble in water and exhibits a molecular formula of C₄H₈N₂O₂. Hydroxyurea functions as a ribonucleotide reductase inhibitor, which disrupts DNA synthesis by preventing the conversion of ribonucleotides to deoxyribonucleotides, thereby inhibiting cell proliferation. The compound is also known for its ability to increase fetal hemoglobin levels in patients with sickle cell disease, which can reduce the frequency of painful crises. Hydroxyurea is typically administered orally and may have side effects, including myelosuppression, gastrointestinal disturbances, and potential teratogenic effects, necessitating careful monitoring during treatment. Its mechanism of action and therapeutic applications make it a significant agent in oncology and hematology.

Formula: CH₄N₂O₂

InChI: InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)

InChI key: InChIKey=VSNHCAURESNICA-UHFFFAOYSA-N

SMILES: O=C(N)NO

Synonyms:

• 1-Hydroxyurea
• Amino(Oxido-Λ5-Azanyl)Methanone
• Biosupressin
• Carbamohydroxamic acid
• Carbamohydroximic acid
• Carbamoyl oxime
• Carbamyl hydroxamate
• Cytodrox
• Droxia
• HU
• Hidrix
• Hidroxicarbamida
• Hydrea
• Hydreia
• Hydrixycarbamide
• Hydroxy Urea (D4)
• Hydroxy urea
• Hydroxycarbamid
• Hydroxycarbamide
• Hydroxycarbamine
• Hydroxylamine, N-(aminocarbonyl)-
• Hydroxylurea
• Hydura
• Hydurea
• Litaler
• Litalir
• Mylocel
• N-(aminocarbonyl)hydroxylamine
• N-Carbamoylhydroxylamine
• N-Hydroxyharnstoff
• N-Hydroxyurea
• Nci C04831
• Nsc 32065
• Onco-carbide
• Oxyrea
• Oxyurea
• Siklos
• Sk 22591
• Sq 1089
• Urea, N-hydroxy-
• Urea, hydroxy-
• Wr 83799
• Xromi

Hydroxyurea, 98%

CAS: 127-07-1

Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is …

• Formula: CH₄N₂O₂
• Purity: 98%
• Color and Shape: White to cream or yellow, Crystals or powder or crystalline powder
• Molecular weight: 76.06

Hydroxycarbamide

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Purity: 99.6%
• Color and Shape: Off-White
• Molecular weight: 76.02728

Hydroxycarbamide CRS

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Color and Shape: Crystalline Powder. White. Powder.
• Molecular weight: 76.0547

Hydroxyurea

CAS: 127-07-1

Non-aromatic organic derivatives of hydrazine or of hydroxylamine for use as drugs

• Formula: CH₄N₂O₂
• Color and Shape: White Off-White Powder
• Molecular weight: 76.06 g/mol

Urea, N-hydroxy-

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 76.05466000000001

Hydroxyurea

CAS: 127-07-1

Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.

• Formula: CH₄N₂O₂
• Purity: 99.85% - 99.92%
• Color and Shape: Solid
• Molecular weight: 76.05

Hydroxy Urea

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Molecular weight: 76.06

Hydroxyurea

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Purity: 98.0 - 102.0 % (anhydrous basis)
• Color and Shape: White to off-white powder
• Molecular weight: 76.06

Hydroxyurea

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Purity: 98%
• Color and Shape: white solid
• Molecular weight: 76.05g/mol

Hydroxyurea, 98%

CAS: 127-07-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: CH₄N₂O₂
• Purity: 98%
• Color and Shape: Crystalline powder, White to almost white
• Molecular weight: 76.06

Hydroxycarbamide

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Color and Shape: Neat
• Molecular weight: 76.05

Hydroxyurea

CAS: 127-07-1

• Formula: CH₄N₂O₂
• Purity: >97.0%(HPLC)(N)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 76.06

Hydroxyurea

CAS: 127-07-1

• Purity: 98.00%
• Color and Shape: Solid, White crystalline powder
• Molecular weight: 76.05500030517578

1-Hydroxyurea

CAS: 127-07-1

• Purity: 95
• Molecular weight: 76.05g/mol

Hydroxy Urea

CAS: 127-07-1

Stability Hygroscopic Applications An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy …

• Formula: CH₄N₂O₂
• Color and Shape: White Solid
• Molecular weight: 76.05

Hydroxyurea

CAS: 127-07-1

Please enquire for more information about Hydroxyurea including the price, delivery time and more detailed …

• Formula: CH₄N₂O₂
• Purity: Min. 97.5 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 76.06 g/mol