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CAS 127-56-0

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Sodium sulfacetamide

Description:
Sodium sulfacetamide is a sulfonamide antibiotic that is primarily used in the treatment of bacterial infections, particularly in ophthalmic formulations for eye infections and as a topical agent for skin conditions like acne. It is a white to off-white crystalline powder that is soluble in water, making it suitable for various pharmaceutical applications. The compound works by inhibiting bacterial growth through the competitive inhibition of the enzyme dihydropteroate synthase, which is essential for the synthesis of folate in bacteria. Sodium sulfacetamide is often combined with other agents to enhance its efficacy and is generally well-tolerated, although some individuals may experience allergic reactions or skin irritation. Its use is contraindicated in patients with a known hypersensitivity to sulfonamides. As with all medications, it is important to use sodium sulfacetamide under the guidance of a healthcare professional to ensure safety and effectiveness.
Formula:C8H10N2O3S·Na
InChI:InChI=1S/C8H10N2O3S.Na/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;/h2-5H,9H2,1H3,(H,10,11);
InChI key:InChIKey=BTZCSADPJAPUNE-UHFFFAOYSA-N
SMILES:S(NC(C)=O)(=O)(=O)C1=CC=C(N)C=C1.[Na]
Synonyms:
  • Acetamide, N-[(4-aminophenyl)sulfonyl]-, monosodium salt
  • Acetamide, N-sulfanilyl-, monosodium salt
  • Acetamide, N-sulfanilyl-, sodium deriv.
  • Albucid soluble
  • Albucide
  • Almocetamide
  • Andremide
  • Antebor
  • Beocid-Isoptal
  • Bleph 10
  • See more synonyms
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