CAS 127-79-7

Sulfamerazine

Description:

Sulfamerazine is a sulfonamide antibiotic that belongs to the class of sulfa drugs, which are synthetic antimicrobial agents. It is characterized by its ability to inhibit bacterial growth by interfering with the synthesis of folic acid, a vital nutrient for bacteria. The chemical structure of sulfamerazine includes a sulfonamide group, which is essential for its antibacterial activity. It is typically administered in the form of its sodium salt and is known for its moderate solubility in water. Sulfamerazine is primarily used in veterinary medicine, particularly for treating infections in livestock and pets. Its pharmacological properties include a relatively long half-life, allowing for less frequent dosing. However, like other sulfonamides, it may cause side effects such as allergic reactions or gastrointestinal disturbances in some individuals. Due to the emergence of antibiotic resistance, the use of sulfamerazine and similar antibiotics is often approached with caution, emphasizing the need for responsible use in both human and veterinary medicine.

Formula: C₁₁H₁₂N₄O₂S

InChI: InChI=1S/C11H12N4O2S/c1-8-6-7-13-11(14-8)15-18(16,17)10-4-2-9(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

InChI key: InChIKey=QPPBRPIAZZHUNT-UHFFFAOYSA-N

SMILES: S(NC=1N=C(C)C=CN1)(=O)(=O)C2=CC=C(N)C=C2

Synonyms:

• 2-(4-Aminobenzenesulfonamido)-4-methylpyrimidine
• 2-Sulfa-4-methylpyrimidine
• 2-Sulfanilamido-4-methylpyrimidine
• 2-Sulfanylamido-4-methylpyrimidine
• 2-Sulphanilamido-4-methylpyrimidine
• 2632Rp
• 2643Rp
• 4-Amino-N-(4-methyl-2-pyrimidinyl)benzenesulfonamide
• 4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide
• A 310
• Benzenesulfonamide, 4-Amino-N-(4-Methyl- 2-Pyrimidinyl)-
• Cremomerazine
• Debenal-M
• Kelamerazine
• Mebacid
• Mesulfa
• Methylpyrimal
• Methylsulfazine
• Metilsulfadiazin
• Metilsulfazin
• N-(4-Methyl-2-pyrimidyl)sulfanilamide
• N-(4-Methylpyrimidin-2-yl)-4-aminobenzenesulfonamide
• N1-(4-Methyl-2-pyrimidinyl)sulfanilamide
• N1-(4-methylpyrimidin-2-yl)sulphanilamide
• N¹-(4-Methyl-2-pyrimidinyl)sulfanilamide
• Nsc 27259
• Percoccide
• Pirimal-M
• Pyralcid
• Pyrimal m
• Romezin
• Rp 2632
• Septacil
• Spanbolet II
• Sulfameradine
• Sulfamerazin
• Sulfamerazina
• Sulfamerazine
• Sulfamerazine Ph Fr-Fu-Usp
• Sulfamerazine solution
• Sulfamethyldiazine
• Sulfanilamide, N1-(4-methyl-2-pyrimidinyl)-
• Sulfanilamide, N¹-(4-methyl-2-pyrimidinyl)-
• Sulphamerazine
• Sumedine

Sulfamerazine N1-Glucuronide

Controlled Product

CAS: 127-79-7

Applications Sulfamerazine N1-Glucuronide, is the metabolite of Sulfamerazine (S689000), acting as an antibacterial.
References Woolfenden, R.D.G., et al.: Anal. Profiles Drug Subs., 6, 515 (1977);

Formula: C₁₇H₂₀N₄O₈S

Color and Shape: Neat

Molecular weight: 440.428

Ref: TR-S688995

Sulfamerazine

Controlled Product

CAS: 127-79-7

Formula: C₁₁H₁₂N₄O₂S

Color and Shape: Neat

Molecular weight: 264.3

Ref: TR-S689000

Sulfamerazine (Sulfadimidine EP Impurity A)

CAS: 127-79-7

Formula: C₁₁H₁₂N₄O₂S

Molecular weight: 264.30

Ref: 4Z-S-244001

Sulfamerazine

CAS: 127-79-7

4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide

Formula: C₁₁H₁₂N₄O₂S

Purity: 98%

Molecular weight: 264.3

Ref: IN-DG78625

Sulfamerazine

CAS: 127-79-7

Formula: C₁₁H₁₂N₄O₂S

Molecular weight: 264.3

Ref: ST-EA-CP-S105000

Sulfamerazine

CAS: 127-79-7

Formula: C₁₁H₁₂N₄O₂S

Color and Shape: Solid

Molecular weight: 264.31

Ref: BE-RMCS202000

Sulfamerazine

CAS: 127-79-7

Formula: C₁₁H₁₂N₄O₂S

Color and Shape: Solid

Molecular weight: 264.31

Ref: BE-BePure-25677

Sulfamerazine in Methanol

CAS: 127-79-7

Methanol

Formula: C₁₁H₁₂N₄O₂S

Color and Shape: Solid

Molecular weight: 264.31

Ref: BE-BePure-25677YM-1000

Sulfamerazine in Methanol

CAS: 127-79-7

Methanol

Formula: C₁₁H₁₂N₄O₂S

Color and Shape: Solid

Molecular weight: 264.31

Ref: BE-BePure-25677XM-100

4-amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide

CAS: 127-79-7

Formula: C₁₁H₁₂N₄O₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 264.3

Ref: 10-F375115

4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide

CAS: 127-79-7

4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide (AMBPS) is a sulfonamide antimicrobial agent that belongs to the group of sulfa drugs. It is a potent inhibitor of tetracycline resistance in bacterial cells, and has been shown to be effective against infectious diseases such as tuberculosis, leprosy and pneumonia. AMBPS has also been used in wastewater treatment and biological studies with high values. This drug binds to sulfamerazine, which inhibits bacterial growth by inhibiting RNA synthesis. The hydrogen bonding interactions between AMBPS and sulfadiazine are thought to be responsible for the effects on congestive heart failure.

Formula: C₁₁H₁₂N₄O₂S

Purity: Min. 95%

Molecular weight: 264.3 g/mol

Ref: 3D-FA133240