CAS 127-88-8

N,N-Bis(2-chloroethyl)phosphoramidic dichloride

Description:

N,N-Bis(2-chloroethyl)phosphoramidic dichloride, with the CAS number 127-88-8, is a chemical compound characterized by its phosphoramidic structure, which includes a phosphorus atom bonded to two chloroethyl groups and a dichloride functional group. This compound is typically a colorless to pale yellow liquid and is known for its reactivity, particularly due to the presence of the chloroethyl groups, which can participate in nucleophilic substitution reactions. It is primarily used in organic synthesis and as an intermediate in the production of various phosphorus-containing compounds. The compound is also recognized for its potential applications in the field of agrochemicals and as a chemical warfare agent, necessitating careful handling and storage due to its toxic and hazardous nature. Safety precautions are essential when working with this substance, as it can pose health risks through inhalation or skin contact. Proper protective equipment and adherence to safety protocols are crucial in any laboratory or industrial setting where this chemical is utilized.

Formula: C₄H₈Cl₄NOP

InChI: InChI=1S/C4H8Cl4NOP/c5-1-3-9(4-2-6)11(7,8)10/h1-4H2

InChI key: InChIKey=IQPMYTNILJQKBS-UHFFFAOYSA-N

SMILES: N(P(Cl)(Cl)=O)(CCCl)CCCl

Synonyms:

• (N,N-Di-2-chloroethyl) phosphoramidic dichloride
• 2-Chloro-N-(2-chloroethyl)-N-dichlorophosphorylethanamine
• Bis(2-chloroethyl)aminophosphonic dichloride
• Bis(2-chloroethyl)aminophosphoric dichloride
• Bis(2-chloroethyl)aminophosphoryl dichloride
• N,N-Bis(2-chloroethyl)phosphamide dichloride
• N,N-Bis(2-chloroethyl)phosphoramidic dichloride
• NSC 64119
• Phosphoramidic dichloride, N,N-bis(2-chloroethyl)-
• Phosphoramidic dichloride, bis(2-chloroethyl)-
• Bis(2-chloroethyl)phosphoramidic dichloride

Phosphoramidic dichloride, N,N-bis(2-chloroethyl)-

CAS: 127-88-8

Formula: C₄H₈Cl₄NOP

Purity: 95%

Color and Shape: Solid

Molecular weight: 258.8982

Ref: IN-DA000WJI

Bis(2-chloroethyl)phosphoramidic Dichloride

CAS: 127-88-8

Formula: C₄H₈Cl₄NOP

Purity: >98.0%(GC)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 258.89

Ref: 3B-B5908

Bis(2-chloroethyl)phosphoramidic dichloride

CAS: 127-88-8

Purity: 98%

Molecular weight: 258.8900146484375

Ref: 10-F752741

Bis(2-chloroethyl)aminophosphoric Dichloride

Controlled Product

CAS: 127-88-8

Applications An intermediate for the synthesis of antitumor drugs used in chemotherapy
References Foster, A.B., et al.: J. Med. Chem., 24, 1399 (1981), Sorsa, M., et al.: Mutat. Res. Genet. Toxicol., 204, 465 (1988),

Formula: C₄H₈Cl₄NOP

Color and Shape: Neat

Molecular weight: 258.90

Ref: TR-B418810

Bis(2-chloroethyl)aminophosphoric dichloride

CAS: 127-88-8

Bis(2-chloroethyl)aminophosphoric dichloride is a fatty acid ester that is used as an antibiotic. It binds to the fatty acid of the bacterial cell membrane, thereby inhibiting the production of vital cell components. Bis(2-chloroethyl)aminophosphoric dichloride has been shown to be active against chondrosarcoma cells in rats and tumor tissue in mice. This drug also inhibits bacterial growth by binding to the fatty acids on the surface of Gram-positive bacteria, such as subtilis and staphylococci. Bis(2-chloroethyl)aminophosphoric dichloride has been shown to have antibacterial activity against Gram-negative bacteria, including Escherichia coli and Salmonella enterica serotype Typhimurium. The binding constants for this drug are high for both Gram-positive and Gram-negative bacteria; however, it does not bind to sugar alcohols or l12

Formula: C₄H₈Cl₄NOP

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 258.9 g/mol

Ref: 3D-FB18667

Cyclophosphamide Impurity 13

CAS: 127-88-8

Formula: C₄H₈Cl₄NOP

Molecular weight: 258.89

Ref: ST-EA-CP-C37023