CAS 127040-01-1
:Troglitazone Impurity 2 (Troglitazone Glucuronide)
Description:
Troglitazone Impurity 2, also known as Troglitazone Glucuronide, is a chemical compound associated with the pharmaceutical agent troglitazone, which was used in the treatment of type 2 diabetes. This impurity is a metabolite formed through the glucuronidation process, where a glucuronic acid moiety is conjugated to the parent compound, enhancing its solubility and facilitating excretion. The compound is characterized by its molecular structure, which includes a glucuronic acid unit linked to the troglitazone framework. Troglitazone itself is a thiazolidinedione, a class of drugs that act as agonists for peroxisome proliferator-activated receptor gamma (PPAR-γ), influencing glucose and lipid metabolism. The presence of impurities like Troglitazone Glucuronide is significant in pharmaceutical development and quality control, as they can affect the efficacy and safety profiles of the drug. Understanding the characteristics and behavior of such impurities is crucial for ensuring the therapeutic integrity of medications.
Formula:C30H35NO11S
Synonyms:- Troglitazone Impurity 2 (Troglitazone Glucuronide)
- β-D-Glucopyranosiduronic acid, 2-[[4-[(2,4-dioxo-5-thiazolidinyl)methyl]phenoxy]methyl]-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-yl
- Troglitazone Glucuronide
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