CAS 127060-75-7

N~6~-{N~2~-[(benzyloxy)carbonyl]-N~5~-(diaminomethylidene)-L-ornithyl}-N~2~-[N-(pyridin-3-ylcarbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-L-isoleucine

Description:

The chemical substance with the name "N~6~-{N~2~-[(benzyloxy)carbonyl]-N~5~-(diaminomethylidene)-L-ornithyl}-N~2~-[N-(pyridin-3-ylcarbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-L-isoleucine" and CAS number 127060-75-7 is a complex peptide derivative. It features multiple amino acid residues, including ornithine, lysine, histidine, proline, and isoleucine, which contribute to its structural and functional properties. The presence of benzyloxycarbonyl and pyridin-3-ylcarbonyl groups indicates that it has been modified for enhanced stability or bioactivity. This compound may exhibit specific biological activities, potentially related to its interactions with biological receptors or enzymes, making it of interest in pharmaceutical research. Its intricate structure suggests potential applications in drug design, particularly in targeting specific pathways or conditions. However, detailed studies would be necessary to fully elucidate its pharmacological properties and mechanisms of action. As with many peptides, its solubility, stability, and reactivity can vary based on environmental conditions and modifications.

Formula: C₅₂H₆₉N₁₃O₁₁

InChI: InChI=1/C52H69N13O11/c1-3-32(2)43(50(73)74)64-48(71)42-17-11-25-65(42)49(72)41(27-36-29-56-31-59-36)62-46(69)39(60-47(70)40(26-33-18-20-37(66)21-19-33)61-44(67)35-14-9-22-55-28-35)15-7-8-23-57-45(68)38(16-10-24-58-51(53)54)63-52(75)76-30-34-12-5-4-6-13-34/h4-6,9,12-14,18-22,28-29,31-32,38-43,66H,3,7-8,10-11,15-17,23-27,30H2,1-2H3,(H,56,59)(H,57,68)(H,60,70)(H,61,67)(H,62,69)(H,63,75)(H,64,71)(H,73,74)(H4,53,54,58)/t32-,38-,39-,40-,41-,42-,43-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)N=C([C@H](CCCCN=C([C@H](CCCNC(=N)N)N=C(O)OCc1ccccc1)O)N=C([C@H](Cc1ccc(cc1)O)N=C(c1cccnc1)O)O)O)O

Angiotensin II Receptor Ligand

CAS: 127060-75-7

Depending on concentrations, CGP-42112 acts as a selective agonist or antagonist of AT₂ receptor-mediated effects.

Formula: C₅₂H₆₉N₁₃O₁₁

Purity: 98.2%

Color and Shape: Yellowish Powder

Molecular weight: 1052.2

Ref: 01-4015751

CGP 42112

CAS: 127060-75-7

Formula: C₅₂H₆₉N₁₃O₁₁

Purity: 98%

Molecular weight: 1052.1848

Ref: IN-DA009ADU

(2S,3S)-2-((S)-1-((5S,12S,15S)-15-((1H-Imidazol-5-yl)methyl)-5-(3-guanidinopropyl)-12-((S)-3-(4-hydroxyphenyl)-2-(nicotinamido)propanamido)-3,6,13-trioxo-1-phenyl-2-oxa-4,7,14-triazahexadecan-16-oyl)p

CAS: 127060-75-7

(2S,3S)-2-((S)-1-((5S,12S,15S)-15-((1H-Imidazol-5-yl)methyl)-5-(3-guanidinopropyl)-12-((S)-3-(4-hydroxyphenyl)-2-(nicotinamido)propanamido)-3,6,13-trioxo-1-phenyl-2-oxa-4,7,14-triazahexadecan-16-oyl)p

Purity: 98%

Molecular weight: 1052.2g/mol

Ref: 54-OR1062962

CGP-42112A

CAS: 127060-75-7

Formula: C₅₂H₆₉N₁₃O₁₁

Molecular weight: 1052.18

Ref: 7W-GK1642

CGP-42112

CAS: 127060-75-7

CGP-42112 is an agonist of the Angiotensin-II subtype 2 receptor (AT2 R).

Formula: C₅₂H₆₉N₁₃O₁₁

Color and Shape: White Solid

Molecular weight: 1052.18

Ref: TM-T14939

CGP 42112

CAS: 127060-75-7

CGP 42112 is a peptide that inhibits the binding of ligands to their receptors. It has been shown to be an effective inhibitor of protein interactions and has been used in research tools for the study of protein-protein interactions. CGP 42112 is an activator of the Ligand-gated ion channels and can be used as an antibody for receptor detection. This compound has a high purity with a CAS number 127060-75-7.

Formula: C₅₂H₆₉N₁₃O₁₁

Purity: Min. 95%

Molecular weight: 1,052.2 g/mol

Ref: 3D-PAN-4296-V

Angiotensin II Receptor Ligand Nicotinoyl-Tyr-Lys(Z-Arg)-His-Pro-Ile-OH

CAS: 127060-75-7

Angiotensin II receptor ligand nicotinoyl-tyrosine-arginine-proline-ile (ANGII) is a peptide that acts as a potent angiotensin II receptor agonist. It can be used to anesthetize rats and cause bradykinin b2 receptor activation. ANGII has been shown to inhibit the growth of several types of tumors, such as human melanoma cells, in animal experiments. This drug also has antiangiogenic properties, which may be due to its ability to induce the production of tumor necrosis factor-α (TNF-α).

Formula: C₅₂H₆₉N₁₃O₁₁

Purity: Min. 95%

Molecular weight: 1,052.19 g/mol

Ref: 3D-FA110425