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CAS 127127-26-8

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2-(Trifluoromethyl)norleucine

Description:
2-(Trifluoromethyl)norleucine is an amino acid derivative characterized by the presence of a trifluoromethyl group attached to the nitrogen-containing backbone of norleucine. This compound features a non-polar hydrocarbon chain, which contributes to its hydrophobic properties, while the trifluoromethyl group introduces significant electronegativity and influences its reactivity and interaction with biological systems. The presence of fluorine atoms enhances the compound's stability and lipophilicity, making it of interest in medicinal chemistry and drug design. Additionally, the structural modifications imparted by the trifluoromethyl group can affect the compound's biological activity, potentially influencing protein folding and enzyme interactions. As a synthetic amino acid, 2-(Trifluoromethyl)norleucine can be utilized in various research applications, including studies on peptide synthesis and the development of fluorinated pharmaceuticals. Its unique properties make it a valuable tool in the exploration of structure-activity relationships in drug development.
Formula:C7H12F3NO2
InChI:InChI=1S/C7H12F3NO2/c1-2-3-4-6(11,5(12)13)7(8,9)10/h2-4,11H2,1H3,(H,12,13)
InChI key:InChIKey=OAWIVBGWGYNPOM-UHFFFAOYSA-N
SMILES:C(CCCC)(C(F)(F)F)(C(O)=O)N
Synonyms:
  • 2-Amino-2-(trifluoromethyl)hexanoic acid
  • Norleucine, 2-(trifluoromethyl)-
  • DL-α-(Trifluoromethyl)norleucine
  • 2-(Trifluoromethyl)norleucine
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