CAS 1271930-12-1

Cinacalcet Impurity 76 HCl (Mixture of Diastereomers)

CAS: 1271930-12-1

Formula: C₂₂H₂₈F₃N·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 363.47 36.46

Ref: 4Z-C-4021

Cinacalcet EP Impurity F

CAS: 1271930-12-1

Formula: C₂₂H₂₈F₃N

Molecular weight: 363.5

Ref: ST-EA-CP-C21042

Hexahydrophenyl Cinacalcet

Controlled Product

CAS: 1271930-12-1

Stability Hygroscopic
Applications Hexahydrophenyl Cinacalcet is an impurity of Cinacalcet Hydrochloride (C441800); a calcimimetic agent and calcium-sensing receptor antagonist.
References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003); Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004); Shinde, G.B., et al.: Org. Process Res. Dev., 15, 455 (2011)

Formula: C₂₂H₂₈F₃N

Color and Shape: Neat

Molecular weight: 363.46

Ref: TR-H291100

Hexahydrophenyl cinacalcet hydrochloride

CAS: 1271930-12-1

Hexahydrophenyl cinacalcet hydrochloride (HPC) is a synthetic compound that is used as an impurity standard in the manufacture of other drugs. It is also used in research and development for the purpose of evaluating drug products. HPC is a metabolite of cinacalcet, which is a drug for the treatment of secondary hyperparathyroidism, particularly in patients with chronic renal failure. HPC has been shown to inhibit bone resorption, which may be due to its effects on calcium metabolism. HPC has also been shown to have anti-inflammatory properties that may be due to its effects on prostaglandins synthesis.

Formula: C₂₂H₂₈F₃N

Purity: Min. 95%

Molecular weight: 363.50 g/mol

Ref: 3D-WAC93012