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CAS 127199-13-7

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(1R,2R)-2-Fluorocyclopropanecarboxylic acid

Description:
(1R,2R)-2-Fluorocyclopropanecarboxylic acid is a fluorinated cyclopropane derivative characterized by its unique three-membered carbon ring structure, which imparts distinctive chemical properties. The presence of a fluorine atom at the second carbon position enhances its reactivity and polarity, making it a valuable intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. This compound features a carboxylic acid functional group, contributing to its acidity and potential for hydrogen bonding, which can influence its solubility and interaction with biological systems. The stereochemistry indicated by the (1R,2R) configuration suggests specific spatial arrangements of the substituents, which can affect the compound's biological activity and reactivity. Additionally, the cyclopropane ring introduces angle strain, which can lead to increased reactivity compared to more stable cyclic compounds. Overall, (1R,2R)-2-Fluorocyclopropanecarboxylic acid is notable for its unique structural features and potential applications in synthetic chemistry.
Formula:C4H5FO2
InChI:InChI=1S/C4H5FO2/c5-3-1-2(3)4(6)7/h2-3H,1H2,(H,6,7)/t2-,3+/m0/s1
Synonyms:
  • Cyclopropanecarboxylic acid, 2-fluoro-, (1R,2R)-
  • Cyclopropanecarboxylic acid, 2-fluoro-, (1R-cis)-
  • (1R,2R)-2-Fluorocyclopropanecarboxylic acid
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