CAS 127308-98-9

Zamifenacinfumarate

Description:

Zamifenacin fumarate is a pharmaceutical compound primarily used as an anticholinergic agent for the treatment of overactive bladder and related urinary disorders. It functions by inhibiting the action of acetylcholine on muscarinic receptors, thereby reducing involuntary bladder contractions and increasing bladder capacity. The substance is characterized by its ability to selectively target specific receptor subtypes, which helps minimize side effects commonly associated with anticholinergic medications. Zamifenacin fumarate is typically administered orally and is known for its relatively favorable pharmacokinetic profile, including good absorption and metabolism. Its efficacy and safety profile have been evaluated in clinical studies, demonstrating its potential benefits in managing urinary symptoms. As with many medications, it may have side effects, including dry mouth, constipation, and dizziness, which are common to anticholinergic drugs. Overall, Zamifenacin fumarate represents a valuable option in the therapeutic landscape for patients suffering from urinary incontinence and related conditions.

Formula: C₃₁H₃₃NO₇

InChI: InChI=1/C27H29NO3.C4H4O4/c1-3-8-22(9-4-1)27(23-10-5-2-6-11-23)31-24-12-7-16-28(19-24)17-15-21-13-14-25-26(18-21)30-20-29-25;5-3(6)1-2-4(7)8/h1-6,8-11,13-14,18,24,27H,7,12,15-17,19-20H2;1-2H,(H,5,6)(H,7,8)/b;2-1+/t24-;/m1./s1

Piperidine, 1-[2-(1,3-benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)-, (3R)-, (2E)-2-butenedioate (1:1)

CAS: 127308-98-9

Formula: C₃₁H₃₃NO₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 531.5962

Ref: IN-DA000WXF

Zamifenacin fumarate

CAS: 127308-98-9

Zamifenacin fumarate

Purity: ≥98%

Molecular weight: 531.6g/mol

Ref: 54-BUP08764

(R)-3-(Benzhydryloxy)-1-(2-(Benzo[D][1,3]Dioxol-5-Yl)Ethyl)Piperidine Fumarate

CAS: 127308-98-9

(R)-3-(Benzhydryloxy)-1-(2-(Benzo[D][1,3]Dioxol-5-Yl)Ethyl)Piperidine Fumarate

Purity: 98%

Molecular weight: 531.6g/mol

Ref: 54-OR1022882

(R)-3-(Benzhydryloxy)-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)piperidine fumarate

CAS: 127308-98-9

Purity: 98.0%

Molecular weight: 531.225702396

Ref: 10-F549389

Zamifenacin Fumarate

Controlled Product

CAS: 127308-98-9

Formula: C₂₇H₂₉NO₃·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 531.596

Ref: TR-Z150705

Zamifenacin Fumarate

Controlled Product

CAS: 127308-98-9

Zamifenacin fumarate is a muscarinic receptor antagonist that is used to treat overactive bladder. It has been shown to be effective in functional studies using saphenous veins and ileal loops in rats. Zamifenacin fumarate binds to the muscarinic M1 receptor, which is responsible for contraction of smooth muscle in the bladder wall. In guinea-pig trachea, zamifenacin fumarate has been shown to reduce the frequency of contractions induced by acetylcholine and histamine. This drug also binds to muscarinic receptors on bladder urothelium and inhibits the release of chloride ions from these cells, which results in increased urinary output. Zamifenacin fumarate competes with arecaidine for binding to muscarinic receptors, but has a lower affinity than arecaidine.

Formula: C₃₁H₃₃NO₇

Purity: Min. 95%

Molecular weight: 415.52 g/mol

Ref: 3D-CFA30898

Zamifenacin fumarate

CAS: 127308-98-9

Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.

Formula: C₃₁H₃₃NO₇

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 531.6

Ref: TM-T13385