CAS 127408-31-5

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-HYDROXYACETAMIDE

Description:

N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide, with the CAS number 127408-31-5, is a chemical compound characterized by its complex structure, which includes a benzopyran moiety and a cyano group. This compound features a hydroxyl group and an acetamide functional group, contributing to its potential biological activity. The stereochemistry indicated by the (3S,4R) configuration suggests specific spatial arrangements that may influence its interaction with biological targets. Typically, compounds of this nature are investigated for their pharmacological properties, including potential roles in medicinal chemistry, such as anti-inflammatory or anticancer activities. The presence of multiple functional groups allows for diverse reactivity and solubility characteristics, which can be tailored for specific applications. As with many organic compounds, its stability, solubility, and reactivity can be influenced by environmental factors such as pH and temperature, making it a subject of interest in both synthetic and applied chemistry research.

Formula: C₁₄H₁₆N₂O₄

InChI: InChI=1/C14H16N2O4/c1-8(17)16(19)12-10-6-9(7-15)4-5-11(10)20-14(2,3)13(12)18/h4-6,12-13,18-19H,1-3H3/t12-,13+/m1/s1

Synonyms:

• Y-26763
• N-[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl]-N-hydroxyacetamide

N-((3S,4R)-6-Cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-hydroxyacetamide

CAS: 127408-31-5

Formula: C₁₄H₁₆N₂O₄

Purity: 99.0%

Molecular weight: 276.2878

Ref: IN-DA000X21

Y-26763

CAS: 127408-31-5

Y-26763 is a drug that blocks ATP-sensitive potassium channels. It has been shown to decrease intracellular calcium concentrations in isolated smooth muscle cells and inhibit the release of acetylcholine from atropine-sensitive sites. In studies with dogs, Y-26763 has shown a potent antihypertensive effect and caused a dose-dependent decrease in blood pressure. Y-26763 is not active against dry weight or whole body weight changes, but it does have an effect on bladder function. The mechanism of action is unknown, but may be related to the inhibition of ATP sensitive potassium channels.

Formula: C₁₄H₁₆N₂O₄

Purity: Min. 95%

Molecular weight: 276.29 g/mol

Ref: 3D-CFA40831

Y-26763

CAS: 127408-31-5

Y-26763 is a K+ channel opener and active metabolite of Y-27152. This is an ATP-sensitive K+ (KATP) channel activator.

Formula: C₁₄H₁₆N₂O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 276.29

Ref: TM-T17268