Conantokin-T is a peptide derived from the venom of the cone snail species Conus tulipa. It is characterized by its unique structure, which includes a series of amino acids that contribute to its biological activity. This peptide is known for its potent neurotoxic effects, specifically its ability to selectively block certain types of glutamate receptors, particularly the NMDA receptor. This action can lead to significant alterations in neuronal signaling and has implications for pain modulation and neuroprotection. Conantokin-T has garnered interest in pharmacological research due to its potential therapeutic applications, particularly in the context of neurological disorders. Additionally, its specificity and potency make it a valuable tool for studying receptor function and signaling pathways in the nervous system. The compound's stability and solubility in physiological conditions further enhance its utility in experimental settings. Overall, conantokin-T represents a fascinating example of how natural products can influence biochemical pathways and contribute to our understanding of neurobiology.

conantokin-T

127476-26-0: Conantokin-T is a peptide derived from the venom of the cone snail species Conus tulipa. It is characterized by its unique structure, which includes a series of amino acids that contribute to its biological activity. This peptide is known for its potent neurotoxic effects, specifically its ability to selectively block certain types of glutamate receptors, particularly the NMDA receptor. This action can lead to significant alterations in neuronal signaling and has implications for pain modulation and neuroprotection. Conantokin-T has garnered interest in pharmacological research due to its potential therapeutic applications, particularly in the context of neurological disorders. Additionally, its specificity and potency make it a valuable tool for studying receptor function and signaling pathways in the nervous system. The compound's stability and solubility in physiological conditions further enhance its utility in experimental settings. Overall, conantokin-T represents a fascinating example of how natural products can influence biochemical pathways and contribute to our understanding of neurobiology.

<p>Non-competitive NMDA receptor antagonist</p>

Conantokin-T

<p>Conantokin-T is a peptide which activates the G protein-coupled receptor, and has been shown to be an inhibitor of ion channels. It binds to the ligand binding domain of certain receptors, such as GABA receptors, and activates them by increasing the affinity of the ligand for the receptor. Conantokin-T has also been shown to inhibit ligand binding to calcium channels.</p>

CAS 127476-26-0

conantokin-T

Conantokin-T

Ref: TM-TP2235

Conantokin-T

Ref: 3D-CFA47626