CAS 127502-06-1

Tetrofosmin

Description:

Tetrofosmin is a chemical compound primarily used as a radiopharmaceutical in medical imaging, particularly in myocardial perfusion imaging. It is a lipophilic cationic compound that facilitates the visualization of cardiac tissues by accumulating in viable myocardial cells. Tetrofosmin is characterized by its ability to cross cell membranes due to its lipophilic nature, allowing it to concentrate in areas with high metabolic activity, such as healthy heart tissue. The compound is typically administered intravenously and is labeled with a radioactive isotope, commonly technetium-99m, which enables its detection through gamma cameras during imaging procedures. Tetrofosmin is known for its favorable pharmacokinetics, including rapid clearance from the bloodstream and minimal retention in non-target tissues, which enhances the quality of the imaging results. Additionally, it has a good safety profile, with a low incidence of adverse effects, making it a valuable tool in the assessment of coronary artery disease and other cardiac conditions.

Formula: C₁₈H₄₀O₄P₂

InChI: InChI=1S/C18H40O4P2/c1-5-19-9-13-23(14-10-20-6-2)17-18-24(15-11-21-7-3)16-12-22-8-4/h5-18H2,1-4H3

InChI key: InChIKey=QCWJONLQSHEGEJ-UHFFFAOYSA-N

SMILES: P(CCP(CCOCC)CCOCC)(CCOCC)CCOCC

Synonyms:

• 3,12-Dioxa-6,9-diphosphatetradecane, 6,9-bis(2-ethoxyethyl)-
• 6,9-Bis(2-Ethoxyethyl)-3,12-Dioxa-6,9-Diphosphatetradecane
• Ethylenebis(bis(2-ethoxyethyl)phosphine)
• Technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
• Tetrofosmin [USAN:INN:BAN:JAN]
• Unii-3J0Kpb596Q
• P 53 (tetrofosmin)
• Tetrofosmin

6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane

CAS: 127502-06-1

Formula: C₁₈H₄₀O₄P₂

Molecular weight: 382.4553

Ref: IN-DA000X4O

Tetrofosmin

CAS: 127502-06-1

Tetrofosmin is a phosphine developed to overcome the non-target uptake of radioligands by the generation of hetero-atomic compounds.

Formula: C₁₈H₄₀O₄P₂

Color and Shape: Solid

Molecular weight: 382.46

Ref: TM-T34830

Tetrofosmin

Controlled Product

CAS: 127502-06-1

Formula: C₁₈H₄₀O₄P₂

Color and Shape: Neat

Molecular weight: 382.455

Ref: TR-T309530