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CAS 127502-06-1

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Tetrofosmin

Description:
Tetrofosmin is a chemical compound primarily used as a radiopharmaceutical in medical imaging, particularly in myocardial perfusion imaging. It is a lipophilic cationic compound that facilitates the visualization of cardiac tissues by accumulating in viable myocardial cells. Tetrofosmin is characterized by its ability to cross cell membranes due to its lipophilic nature, allowing it to concentrate in areas with high metabolic activity, such as healthy heart tissue. The compound is typically administered intravenously and is labeled with a radioactive isotope, commonly technetium-99m, which enables its detection through gamma cameras during imaging procedures. Tetrofosmin is known for its favorable pharmacokinetics, including rapid clearance from the bloodstream and minimal retention in non-target tissues, which enhances the quality of the imaging results. Additionally, it has a good safety profile, with a low incidence of adverse effects, making it a valuable tool in the assessment of coronary artery disease and other cardiac conditions.
Formula:C18H40O4P2
InChI:InChI=1S/C18H40O4P2/c1-5-19-9-13-23(14-10-20-6-2)17-18-24(15-11-21-7-3)16-12-22-8-4/h5-18H2,1-4H3
InChI key:InChIKey=QCWJONLQSHEGEJ-UHFFFAOYSA-N
SMILES:P(CCP(CCOCC)CCOCC)(CCOCC)CCOCC
Synonyms:
  • 3,12-Dioxa-6,9-diphosphatetradecane, 6,9-bis(2-ethoxyethyl)-
  • 6,9-Bis(2-Ethoxyethyl)-3,12-Dioxa-6,9-Diphosphatetradecane
  • Ethylenebis(bis(2-ethoxyethyl)phosphine)
  • Technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
  • Tetrofosmin [USAN:INN:BAN:JAN]
  • Unii-3J0Kpb596Q
  • P 53 (tetrofosmin)
  • Tetrofosmin
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