CAS 127512-29-2: DODAP

Description: DODAP, or dioctadecyldimethylammonium phosphate, is a quaternary ammonium compound characterized by its long hydrophobic alkyl chains and a positively charged ammonium group. It is typically used as a surfactant and emulsifying agent due to its amphiphilic nature, which allows it to interact with both hydrophilic and hydrophobic substances. DODAP is known for its ability to form stable lipid bilayers and is often utilized in the formulation of liposomes and other nanocarriers for drug delivery applications. Its structure contributes to its effectiveness in encapsulating hydrophobic drugs, enhancing their solubility and bioavailability. Additionally, DODAP exhibits biocompatibility, making it suitable for pharmaceutical and biomedical applications. However, like many quaternary ammonium compounds, it may also possess antimicrobial properties, which can be advantageous in certain formulations. Overall, DODAP's unique properties make it a valuable compound in various fields, including pharmaceuticals, cosmetics, and materials science.

Formula: C₄₁H₇₇NO₄

InChI: InChI=1/C41H77NO4/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40(43)45-38-39(37-42(3)4)46-41(44)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h19-22,39H,5-18,23-38H2,1-4H3/b21-19-,22-20-

Synonyms:

• 18:1 Dap
• 1,2-Dioleoyloxy-3-(Dimethylamino)Propane
• 1,2-Dioleoyl-3-Dimethylammonium-Propane
• 3-(dimethylamino)propane-1,2-diyl (9Z,9'Z)bis-octadec-9-enoate

9-Octadecenoic acid (9Z)-, 1,1'-[1-[(dimethylamino)methyl]-1,2-ethanediyl] ester

CAS: 127512-29-2

• Formula: C₄₁H₇₇NO₄
• Purity: 98%
• Color and Shape: Liquid
• Molecular weight: 648.0543800000003

1,2-Dioleoyloxy-3-(dimethylamino)propane

CAS: 127512-29-2

• Formula: C41H77NO4
• Purity: >98%
• Color and Shape: Solid
• Molecular weight: 648.06

DODAP

CAS: 127512-29-2

DODAP is a cationic lipid crucial for making liposomes, encapsulating siRNA, and delivering immunostimulatory drugs …

• Formula: C₄₁H₇₇NO₄
• Color and Shape: Liquid
• Molecular weight: 648.05

1,2-Dioleoyloxy-3-(dimethylamino)propane

CAS: 127512-29-2

Applications Cationic amphiphiles are being studied for their potential role in preparing liposomes for interaction …

• Formula: C₄₁H₇₇NO₄
• Color and Shape: Neat
• Molecular weight: 648.05

1,2-Dioleoyloxy-3-(dimethylamino)propane

CAS: 127512-29-2

DODAP; positively charged cell membrane phospholipid

• Formula: C₄₁H₇₇NO₄
• Purity: Min. 95%
• Molecular weight: 648.05 g/mol