CAS 1276110-06-5

HS-173

Description:

HS-173, with the CAS number 1276110-06-5, is a chemical compound that has garnered attention in various fields, particularly in research and development. While specific characteristics such as its molecular formula, structure, and physical properties may vary, HS-173 is typically recognized for its role as a potential therapeutic agent or research tool. It may exhibit properties such as solubility in organic solvents, stability under certain conditions, and specific reactivity with biological targets. The compound's safety profile, including toxicity and handling precautions, is crucial for its application in laboratory settings. As with many chemical substances, detailed characterization through methods like spectroscopy and chromatography is essential for understanding its behavior and potential uses. Researchers often explore its efficacy in biological assays, making it relevant in pharmacological studies. For precise applications and safety measures, consulting specific material safety data sheets (MSDS) and peer-reviewed literature is recommended.

Imidazo[1,2-a]pyridine-3-carboxylic acid, 6-[5-[(phenylsulfonyl)amino]-3-pyridinyl]-, ethyl ester

CAS: 1276110-06-5

Formula: C₂₁H₁₈N₄O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 422.4570

Ref: IN-DA000X80

Ethyl 6-(5-(Phenylsulfonamido)Pyridin-3-Yl)Imidazo[1,2-A]Pyridine-3-Carboxylate

CAS: 1276110-06-5

Ethyl 6-(5-(Phenylsulfonamido)Pyridin-3-Yl)Imidazo[1,2-A]Pyridine-3-Carboxylate

Purity: 97%

Molecular weight: 422.46g/mol

Ref: 54-OR1025916

HS-173

CAS: 1276110-06-5

HS-173

Purity: ≥98%

Molecular weight: 422.46g/mol

Ref: 54-BUP03764

HS-173

CAS: 1276110-06-5

HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).

Formula: C₂₁H₁₈N₄O₄S

Purity: 99.33% - 99.64%

Color and Shape: Solid

Molecular weight: 422.46

Ref: TM-T2308

HS-173

Controlled Product

CAS: 1276110-06-5

Applications HS-173 is a potent PI3Kα inhibitor with anticancer activity.
References Kim, O., et al.: J. Med. Chem., 54, 2455 (2011); Lee, H., et al.: Cancer Lett., 328, 152 (2013)

Formula: C₂₁H₁₈N₄O₄S

Color and Shape: Neat

Molecular weight: 422.46

Ref: TR-H671500

HS-173

CAS: 1276110-06-5

HS-173 is a synthetic nucleoside analog that has transcription-polymerase chain inhibitory activity. HS-173 inhibits the expression of genes by binding to the major groove of DNA and blocking the progression of transcription. This drug also induces autophagy to eliminate damaged or dysfunctional cells, as well as regulating cell proliferation and differentiation. In addition, HS-173 has been shown to have synergistic effects with epidermal growth factor (EGF) and radiation in hl-60 cells and monoclonal antibody against carcinoembryonic antigen in k562 cells.

Formula: C₂₁H₁₈N₄O₄S

Purity: Min. 95%

Molecular weight: 422.46 g/mol

Ref: 3D-BBC11006