CAS 127634-29-1

beta-neuroprotectin

Description:

Beta-neuroprotectin, also known as neuroprotectin D1 (NPD1), is a bioactive lipid mediator derived from docosahexaenoic acid (DHA), an omega-3 fatty acid. It plays a crucial role in neuroprotection and inflammation resolution within the central nervous system. Characteristically, beta-neuroprotectin exhibits anti-inflammatory properties, promoting cell survival and protecting neurons from apoptosis in various neurodegenerative conditions. It is involved in the regulation of cellular signaling pathways that enhance neuronal resilience and support the maintenance of cellular homeostasis. Additionally, beta-neuroprotectin has been studied for its potential therapeutic applications in conditions such as Alzheimer's disease, stroke, and other neurodegenerative disorders. Its synthesis is typically initiated by the enzymatic conversion of DHA through lipoxygenase pathways, leading to the formation of this potent neuroprotective compound. Overall, beta-neuroprotectin represents a significant area of research in neurobiology, highlighting the importance of lipid mediators in brain health and disease.

Formula: C₃₇H₆₀N₈O₁₀

InChI: InChI=1/C37H60N8O10/c1-9-20(6)30(45-36(54)26(15-19(4)5)44-35(53)28(17-29(47)48)42-32(50)21(7)38)37(55)40-22(8)33(51)43-27(16-23-10-12-24(46)13-11-23)34(52)41-25(31(39)49)14-18(2)3/h10-13,18-22,25-28,30,46H,9,14-17,38H2,1-8H3,(H2,39,49)(H,40,55)(H,41,52)(H,42,50)(H,43,51)(H,44,53)(H,45,54)(H,47,48)/t20-,21+,22-,25-,26-,27-,28-,30-/m0/s1

Synonyms:

• Ala-asp-leu-ile-ala-tyr-leu-NH2
• L-Leucinamide, D-alanyl-L-alpha-aspartyl-L-leucyl-L-isoleucyl-L-alanyl-L-tyrosyl-
• D-alanyl-L-alpha-aspartyl-L-leucyl-L-isoleucyl-L-alanyl-L-tyrosyl-L-leucinamide

β-Neuroprotectin

CAS: 127634-29-1

beta-Neuroprotectin is a (3H)TCP binding inhibitor and provides protection against NMDA mediated neuronal cell death at low concentration.

Formula: C₃₇H₆₀N₈O₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 776.92

Ref: TM-T25148

β-Neuroprotectin

CAS: 127634-29-1

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Formula: C₃₇H₆₀N₈O₁₀

Purity: Min. 95%

Molecular weight: 776.92 g/mol

Ref: 3D-FN111037