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CAS 12771-72-1

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verruculogen from penicillium*verruculosum

Description:
Verruculogen is a mycotoxin produced by the fungus Penicillium verruculosum, classified under the category of indole alkaloids. This compound is characterized by its complex structure, which includes a bicyclic framework and multiple functional groups, contributing to its biological activity. Verruculogen exhibits neurotoxic properties, affecting neurotransmitter release and potentially leading to adverse effects on the nervous system. It has been studied for its potential implications in food safety, as it can contaminate various agricultural products. The compound is also of interest in pharmacological research due to its unique mechanism of action and potential therapeutic applications. However, its toxicity necessitates careful handling and regulation. In terms of solubility, verruculogen is typically soluble in organic solvents, which is common for many mycotoxins. Overall, while verruculogen presents intriguing avenues for research, its toxicological profile underscores the importance of monitoring and controlling its presence in food and feed products.
Formula:C27H33N3O7
InChI:InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1
InChI key:InChIKey=LRXYHMMJJCTUMY-GWXUGYLUSA-N
SMILES:C(=C(C)C)[C@@H]1N2C3=C(C=4C2=CC(OC)=CC4)[C@H](O)[C@]5(O)N([C@]3(CC(C)(C)OO1)[H])C(=O)[C@]6(N(C5=O)CCC6)[H]
Synonyms:
  • (5R,10S,10aR,14aS,15bS)-1,10,10a,14,14a,15b-Hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
  • 10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
  • 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-, (5R,10S,10aR,14aS,15bS)-
  • 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-
  • 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, [5R-(5α,10α,10aα,14aα,15bα)]-
  • Na 209A
  • TR 1 toxin
  • Verruculogen
  • Verruculogen TR 1
  • Verruculogen, Penicillium verruculosum
  • See more synonyms
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Found 7 products.
  • Verruculogen

    CAS:
    Formula:C27H33N3O7
    Purity:98.89%
    Color and Shape:Brownish. Amorphous solid
    Molecular weight:511.0

    Ref: 8R-AD0189

    1mg
    To inquire
    5mg
    To inquire
  • Verruculogen from Penicillium verruculosum

    CAS:
    Verruculogen from Penicillium verruculosum
    Formula:C27H35N3O7
    Purity:By hplc: 97.52% (Typical Value in Batch COA)
    Color and Shape: white powder
    Molecular weight:513.58g/mol

    Ref: 54-BIV1002

    1mg
    182.00€
    5mg
    625.00€
    10mg
    1,111.00€
    25mg
    2,277.00€
    50mg
    4,126.00€
    100mg
    7,483.00€
  • Verruculogen

    CAS:
    Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.
    Formula:C27H33N3O7
    Purity:98%
    Color and Shape:White Powder
    Molecular weight:511.57

    Ref: TM-T13297

    1mg
    225.00€
    5mg
    675.00€
  • Verruculogen

    CAS:
    Formula:C27H33N3O7
    Purity:≥ 95.0%
    Color and Shape:Off-white to brown solid
    Molecular weight:511.6

    Ref: 7W-GL5203

    1mg
    218.00€
    5mg
    612.00€
  • Verruculogen

    CAS:

    Applications Verruculogen is a mycotoxin and novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus.
    Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
    References Cui, C. et al.: Jour. of Ant., 49(6), 527-533, (1996)

    Formula:C27H33N3O7
    Color and Shape:Neat
    Molecular weight:511.57

    Ref: TR-V267190

    1mg
    510.00€
    2500µg
    1,115.00€
    5mg
    1,542.00€
  • Verruculogen

    CAS:
    Verruculogen is a mycotoxin, which is derived from certain species of fungi, primarily those in the genera Aspergillus and Penicillium. It is synthesized by these fungi during their secondary metabolic processes. As a chemical compound, verruculogen acts by inhibiting calcium channels in nerve cells, disrupts neurotransmitter release, and affects neuronal activity. This mode of action is crucial in understanding its role in toxicology and pharmacology.
    Purity:Min. 95%

    Ref: 3D-BV162751

    1mg
    402.00€
    5mg
    1,356.00€
    10mg
    2,114.00€