CAS 1277168-02-1

5-Phenyl-1H-pyrazole-3-sulfonyl chloride

Description:

5-Phenyl-1H-pyrazole-3-sulfonyl chloride is a chemical compound characterized by its sulfonyl chloride functional group, which makes it a reactive intermediate in organic synthesis. This compound features a pyrazole ring, a five-membered heterocyclic structure containing two nitrogen atoms, and a phenyl group, which contributes to its aromatic properties. The presence of the sulfonyl chloride group indicates that it can participate in nucleophilic substitution reactions, making it useful for the synthesis of sulfonamides and other derivatives. It is typically a white to off-white solid and is soluble in organic solvents. Due to its reactivity, it should be handled with care, as sulfonyl chlorides can release hydrochloric acid upon reaction with water or alcohols. This compound is often utilized in pharmaceutical research and development, particularly in the design of biologically active molecules. Proper safety measures should be observed when working with this substance, as it may pose health hazards if inhaled or if it comes into contact with skin.

Formula: C₉H₇ClN₂O₂S

InChI: InChI=1S/C9H7ClN2O2S/c10-15(13,14)9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H,(H,11,12)

InChI key: InChIKey=IBHNCBUMLPNXQE-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C=1C=C(NN1)C2=CC=CC=C2

Synonyms:

• 3-Phenyl-1H-pyrazole-5-sulfonyl chloride
• 5-Phenyl-1H-pyrazole-3-sulfonyl chloride
• 1H-Pyrazole-3-sulfonyl chloride, 5-phenyl-