CAS 12772-57-5: radicicol

Formula: C₁₈H₁₇ClO₆

InChI: InChI=1S/C18H17ClO6/c1-9-6-15-14(25-15)5-3-2-4-10(20)7-11-16(18(23)24-9)12(21)8-13(22)17(11)19/h2-5,8-9,14-15,21-22H,6-7H2,1H3/b4-2+,5-3-/t9-,14-,15-/m1/s1

InChI key: InChIKey=WYZWZEOGROVVHK-GTMNPGAYSA-N

SMILES: O=C1OC(C)CC2OC2C=CC=CC(=O)CC=3C(Cl)=C(O)C=C(O)C13

Synonyms:

• (+)-Monorden A
• (1aR,2E,4E,14R,15aS)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione
• (1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione
• (2E,4E)-8-chloro-9,11-dihydroxy-14-methyl-1a,14,15,15a-tetrahydro-6H-oxireno[e][2]benzoxacyclotetradecine-6,12(7H)-dione
• 6H-Oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione, 8-chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-, (1aR,2Z,4E,14R,15aR)-
• Monorden
• Monordene
• NSC 294404
• Radicicol R 2146
• Radicicol, Diheterospora chlamydosporia
• Radicolol
• Radisicol
• β-Resorcylic acid, 5-chloro-6-(7,8-epoxy-10-hydroxy-2-oxo-3,5-undecadienyl)-, μ-lactone

Radicicol; Radisicol; Monordene; Monorden; RHI-12648; FO-4910. Es igual a MM0001

CAS: 12772-57-5

• Formula: C₁₈H₁₇ClO₆
• Purity: 99.4%
• Color and Shape: yellowish. Solid
• Molecular weight: 364.0

6H-Oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione, 8-chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-, (1aR,2Z,4E,14R,15aR)-

CAS: 12772-57-5

• Formula: C₁₈H₁₇ClO₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 364.7770

Radicicol

CAS: 12772-57-5

Antifungal Radicicol blocks P. falciparum replication, inhibits Hsp90 (IC50: 1μM), leading to proteasomal degradation.

• Formula: C₁₈H₁₇ClO₆
• Purity: 98%
• Color and Shape: White/Yellow Powder
• Molecular weight: 364.78

Radicicol

CAS: 12772-57-5

• Formula: C₁₈H₁₇ClO₆
• Purity: By hplc: 98.77% (Typical Value in Batch COA)
• Color and Shape: yellowish amorphous solid
• Molecular weight: 364.78g/mol

Radicicol

CAS: 12772-57-5

• Formula: C₁₈H₁₇ClO₆
• Purity: ≥ 98.0%
• Color and Shape: White to yellow powder
• Molecular weight: 364.78

Radicicol

CAS: 12772-57-5

Inhibits heat shock protein 90 (HSP90); anti-cancer agent

• Formula: C₁₈H₁₇ClO₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 364.78 g/mol