CAS 127753-52-0
:Thymidine 5′-(tetrahydrogen triphosphate), 3′-azido-3′-deoxy-, compd. with N,N-diethylethanamine (1:3)
Description:
Thymidine 5′-(tetrahydrogen triphosphate), 3′-azido-3′-deoxy-, compd. with N,N-diethylethanamine is a chemical compound that features a modified nucleoside, specifically thymidine, which is a building block of DNA. The presence of the azido group (–N3) indicates that this compound may have applications in bioconjugation and click chemistry, as azides can react with alkynes in a copper-catalyzed reaction to form triazoles. The triphosphate moiety suggests that this compound may be involved in nucleotide metabolism or serve as a substrate for polymerases in nucleic acid synthesis. The inclusion of N,N-diethylethanamine as a counterion or stabilizing agent may influence the solubility and reactivity of the compound. Overall, this substance is of interest in biochemical research, particularly in the fields of molecular biology and medicinal chemistry, where it may be utilized for the development of antiviral agents or in the study of nucleic acid interactions. Its specific properties, such as solubility, stability, and reactivity, would depend on the conditions under which it is used.
Formula:C10H16N5O13P3·3C6H15N
InChI:InChI=1S/C10H16N5O13P3.C6H15N/c1-5-3-15(10(17)12-9(5)16)8-2-6(13-14-11)7(26-8)4-25-30(21,22)28-31(23,24)27-29(18,19)20;1-4-7(5-2)6-3/h3,6-8H,2,4H2,1H3,(H,21,22)(H,23,24)(H,12,16,17)(H2,18,19,20);4-6H2,1-3H3/t6-,7+,8+;/m0./s1
InChI key:InChIKey=HYYLITPZPVPOSS-HNPMAXIBSA-N
SMILES:O=C1N([C@@H]2O[C@H](COP(OP(OP(=O)(O)O)(=O)O)(=O)O)[C@@H](N=[N+]=[N-])C2)C=C(C)C(=O)N1.N(CC)(CC)CC
Synonyms:- Thymidine 5′-(tetrahydrogen triphosphate), 3′-azido-3′-deoxy-, compd. with N,N-diethylethanamine (1:3)
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Found 2 products.
3'-Azido-3'-deoxythymidine 5'-triphosphate triethylammonium salt
CAS:<p>3'-Azido-3'-deoxythymidine 5'-triphosphate triethylammonium salt is a nucleoside analogue of 3'-azido-3'-deoxythymidine. It is an antiviral agent that inhibits the synthesis of viral DNA and RNA by inhibiting the activity of DNA polymerase, which has been shown to be effective against HIV and herpes simplex virus type 1. The phosphoramidites are synthesized from the corresponding phosphonate, 3'-azido-3'-deoxythymidine 5'-triphosphate, by treatment with a base (e.g., sodium methoxide). This novel nucleoside analogue has been shown to have anticancer properties in animal models.</p>Formula:C10H16N5O13P3·3C6H15NPurity:Min. 95%Molecular weight:810.75 g/molRef: 3D-NA15338
Discontinued product
