CAS 127759-89-1

Lobucavir

Description:

Lobucavir, with the CAS number 127759-89-1, is an antiviral compound primarily studied for its potential in treating viral infections, particularly those caused by herpesviruses. It belongs to the class of nucleoside analogs, which function by mimicking the building blocks of nucleic acids, thereby interfering with viral replication. Lobucavir exhibits a unique mechanism of action that involves the inhibition of viral DNA polymerase, making it effective against certain strains of viruses. The compound is characterized by its moderate solubility in water and its stability under physiological conditions, which is crucial for its therapeutic efficacy. Additionally, Lobucavir has been evaluated for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which are essential for determining its suitability as a medication. While research continues to explore its full potential and safety profile, Lobucavir represents a promising candidate in the ongoing search for effective antiviral therapies.

Formula: C₁₁H₁₅N₅O₃

InChI: InChI=1S/C11H15N5O3/c12-11-14-9-8(10(19)15-11)13-4-16(9)7-1-5(2-17)6(7)3-18/h4-7,17-18H,1-3H2,(H3,12,14,15,19)/t5-,6-,7-/m1/s1

InChI key: InChIKey=GWFOVSGRNGAGDL-FSDSQADBSA-N

SMILES: C(O)[C@H]1[C@H](N2C3=C(N=C2)C(=O)N=C(N)N3)C[C@@H]1CO

Synonyms:

• (+)-Cyclobut G
• 2-Amino-9-[(1R,2R,3S)-2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one
• 2-amino-9-[(1R,2R,3S)-2,3-bis(hydroxymethyl)cyclobutyl]-3,9-dihydro-6H-purin-6-one
• 6H-Purin-6-one, 2-amino-9-((1R,2R,3S)-2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro-
• 6H-Purin-6-one, 2-amino-9-(2,3-bis(hydroxymethyl)cyclobutyl)-1,9-dihydro, (1R-(1alpha,2beta,3alpha))
• 6H-Purin-6-one, 2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-, [1R-(1α,2β,3α)]-
• 9-((1R,2R,3S)-2,3-Bis(hydroxymethyl)cyclobutyl)guanine
• A-69992
• Bms-180194
• C-Oxetanocin-G
• Ccris 9309
• Drg-0235
• Lobucavir [USAN:INN]
• Sq 34,514

2-Amino-9-((1R,2R,3S)-2,3-bis(hydroxymethyl)cyclobutyl)-1H-purin-6(9H)-one

CAS: 127759-89-1

Formula: C₁₁H₁₅N₅O₃

Color and Shape: Solid

Molecular weight: 265.2685

Ref: IN-DA000XDI

Lobucavir

CAS: 127759-89-1

Formula: C₁₁H₁₅N₅O₃

Molecular weight: 265.27

Ref: 4Z-L-491

Lobucavir-d4

CAS: 127759-89-1

Formula: C₁₁H₁₁D₄N₅O₃

Molecular weight: 269.30

Ref: 4Z-L-492

Lobucavir

Controlled Product

CAS: 127759-89-1

Applications A nucleoside analog used in the treatment of viral infections, including those caused by human immunodeficiency virus, cytomegalovirus, and herpes virus.
References Faulds, D., et al.: Drugs, 39, 597 (1990), Greene, J., et al.: Fundam. Appl. Toxicol., 32, 140 (1996), Poirier, M., et al.: Toxicol. Appl. Pharmacol., 199, 151 (2004),

Formula: C₁₁H₁₅N₅O₃

Color and Shape: Neat

Molecular weight: 265.27

Ref: TR-L469360

Lobucavir

CAS: 127759-89-1

Lobucavir is an antiviral compound with a mode of action that inhibits viral DNA polymerase. It is used for treating infections caused by herpesviruses and hepatitis B virus.

Formula: C₁₁H₁₅N₅O₃

Purity: Min. 95%

Molecular weight: 265.27 g/mol

Ref: 3D-FA111974

Lobucavir

CAS: 127759-89-1

Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).

Formula: C₁₁H₁₅N₅O₃

Color and Shape: Solid

Molecular weight: 265.27

Ref: TM-T200820