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CAS 127780-16-9

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PANTOPRAZOLE SULPHONE SODIUM SALT

Description:
Pantoprazole sulphone sodium salt is a chemical compound primarily used in the treatment of gastroesophageal reflux disease (GERD) and other conditions related to excessive stomach acid production. It is a derivative of pantoprazole, a proton pump inhibitor that works by inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, thereby reducing gastric acid secretion. The sodium salt form enhances its solubility and bioavailability. Pantoprazole sulphone sodium salt is typically a white to off-white crystalline powder, and it is soluble in water, which facilitates its formulation in oral and injectable dosage forms. The compound is stable under normal conditions but may be sensitive to light and moisture, necessitating proper storage conditions. Its pharmacological profile includes a rapid onset of action and a relatively long duration of effect, making it effective for managing acid-related disorders. As with any medication, potential side effects and contraindications should be considered, and it is essential to use it under medical supervision.
Formula:C16H15F2N3O5S
InChI:InChI=1/C16H15F2N3O5S/c1-24-13-5-6-19-12(14(13)25-2)8-27(22,23)16-20-10-4-3-9(26-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
SMILES:COc1ccnc(CS(=O)(=O)c2nc3ccc(cc3[nH]2)OC(F)F)c1OC
Synonyms:
  • 5-difluoromethoxy-2-((3,4 dimethoxy-2-pyridyl)methylsulfonyl)-1H-benzimidazole
  • 5-Difluoromethoxy-2-[( 3,4-Dimethoxy-2-Pyridinylmethyl Sulfonyl) -1H-Benzimidazole
  • 6-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfonyl}-1H-benzimidazole
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