CAS 127842-54-0

3,4-BIS-DIFLUOROMETHOXY-BENZALDEHYDE

Description:

3,4-Bis-difluoromethoxy-benzaldehyde is an organic compound characterized by the presence of two difluoromethoxy groups attached to a benzaldehyde moiety. This compound features a benzene ring with two substituents: the aldehyde functional group (-CHO) and two difluoromethoxy groups (-OCH2F) at the 3 and 4 positions. The difluoromethoxy groups enhance the compound's electron-withdrawing properties, which can influence its reactivity and interactions in various chemical environments. This compound is typically used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals or agrochemicals. Its unique structure may also impart specific physical properties, such as solubility and boiling point, which are influenced by the presence of fluorine atoms. Additionally, the compound's reactivity can be affected by the electron-withdrawing nature of the difluoromethoxy groups, making it a subject of interest in studies involving electrophilic aromatic substitution and other chemical transformations. Safety data and handling precautions should be observed due to the potential hazards associated with fluorinated compounds.

Formula: C₉H₆F₄O₃

Synonyms:

• 3,4-Bis-difluoromethoxybenzaldehyde

Benzaldehyde, 3,4-bis(difluoromethoxy)-

CAS: 127842-54-0

Formula: C₉H₆F₄O₃

Purity: 98%

Color and Shape: Liquid

Molecular weight: 238.1358

Ref: IN-DA000XG5

3,4-Bis(difluoromethoxy)benzaldehyde

CAS: 127842-54-0

3,4-Bis(difluoromethoxy)benzaldehyde

Purity: 98%

Molecular weight: 238.14g/mol

Ref: 54-PC49211

3,4-Bis(difluoromethoxy)benzaldehyde

CAS: 127842-54-0

Formula: C₉H₆F₄O₃

Purity: 98%

Color and Shape: Liquid

Molecular weight: 238.138

Ref: 10-F216794

3,4-Bis(difluoromethoxy)benzaldehyde

Controlled Product

CAS: 127842-54-0

Applications 3,4-Bis(difluoromethoxy)benzaldehyde is an impurity of the antiasthmatic drug Roflumilast (R639700). 3,4-Bis(difluoromethoxy)benzaldehyde is used in the preparation of diphenylethylene compounds as PDE4 (phosphodiesterase-4) inhibitors for treatment of cancer, CNS disorders, and inflammatory disorders.
References Bender, A., et al.: Pharmacol. Rev., 58, 488 (2006), Huang, Z., et al.: Curr. Med. Chem., 13, 3253 (2006), Lerner, A., et al.: Biochem. J., 393, 21 (2006),

Formula: C₉H₆F₄O₃

Color and Shape: Neat

Molecular weight: 238.14

Ref: TR-B426290

Roflumilast Impurity 15

CAS: 127842-54-0

Formula: C₉H₆F₄O₃

Molecular weight: 238.14

Ref: ST-EA-CP-R29021